The relationship between circulating concentrations of interleukin 17 and C reactive protein in chronic spontaneous urticaria.
In: Allergy, Asthma & Clinical Immunology, Jg. 13 (2017-05-10), S. 1-5
Online
academicJournal
Zugriff:
Background: Up-regulation of interleukin 17 (IL-17) family cytokines and acute phase response have been observed in patients with chronic spontaneous urticaria (CSU). It has been demonstrated that IL-17 stimulates C-reactive protein (CRP) expression. Aim: To determine relationship between circulating concentrations of IL-17 and CRP in CSU. Methods: Concentrations of IL-17 in plasma and CRP in serum were measured in patients with CSU of varying severity and in the healthy subjects. Results: IL-17 and CRP concentrations were significantly higher in CSU patients as compared to the healthy subjects. In addition, there were significant differences in IL-17 and CRP concentrations between CSU patients with mild, moderate-severe symptoms and the healthy subjects. CRP did not correlate significantly with IL-17. Conclusions: Increased circulating IL-17 concentration may represent an independent index of systemic inflammatory response in CSU, which is not related to increased CRP concentration. [ABSTRACT FROM AUTHOR]
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The relationship between circulating concentrations of interleukin 17 and C reactive protein in chronic spontaneous urticaria.
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Autor/in / Beteiligte Person: | Grzanka, A. ; Damasiewicz-Bodzek, A. ; Kasperska-Zajac, A. |
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Zeitschrift: | Allergy, Asthma & Clinical Immunology, Jg. 13 (2017-05-10), S. 1-5 |
Veröffentlichung: | 2017 |
Medientyp: | academicJournal |
ISSN: | 1710-1484 (print) |
DOI: | 10.1186/s13223-017-0197-6 |
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