The acceptability and validity of self-collected nasal swabs for detection of influenza virus infection among older adults in Thailand.
In: Influenza & Other Respiratory Viruses, Jg. 11 (2017-09-01), Heft 5, S. 412-417
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Zugriff:
Background Self-collection of nasal swabs could improve the timeliness of influenza virus detection in older adults. Objectives Measure the acceptability, adequacy, timeliness, and validity of self-collected nasal swabs among adults >65 years in Thailand. Methods Our evaluation consisted of two parts: a one-month study among randomly selected, community-dwelling older adults to simulate community-based surveillance for acute respiratory infections ( ARI); and a clinic study of older adults with ARI to evaluate the sensitivity and specificity of self-collected nasal swabs for influenza virus infection compared with healthcare worker ( HCW)-collected nasal and nasopharyngeal swabs. Results In the community study, 24% of participants experienced an ARI during the observation period. All (100%) participants with an ARI self-collected nasal swabs within 72 hours of symptom onset of which 92% were considered adequate samples. In the clinic study, 45% of patients with ARI presented within 72 hours of symptom onset. The sensitivity of self-collected nasal swabs for detection of influenza virus infection was 78% (95% CI 40-97) compared to nasopharyngeal and 88% (95% CI 47-100) compared to nasal swabs collected by HCWs. Specificity was 100% (95% CI 97-100) compared to both methods. Self-collection of nasal swabs was found acceptable by 99% of participants in both studies. Conclusions Self-collection of nasal swabs was acceptable to older adults in Thailand who were able to take adequate samples. Self-collection of nasal swabs may improve the timeliness of sample collection but lower sensitivity will need to be considered. [ABSTRACT FROM AUTHOR]
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The acceptability and validity of self-collected nasal swabs for detection of influenza virus infection among older adults in Thailand.
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Autor/in / Beteiligte Person: | Goyal, Sonal ; Prasert, Kriengkrai ; Praphasiri, Prabda ; Chittaganpitch, Malinee ; Waicharoen, Sunthareeya ; Ditsungnoen, Darunee ; Jaichuang, Siriluk ; Lindblade, Kim A. |
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Zeitschrift: | Influenza & Other Respiratory Viruses, Jg. 11 (2017-09-01), Heft 5, S. 412-417 |
Veröffentlichung: | 2017 |
Medientyp: | academicJournal |
ISSN: | 1750-2640 (print) |
DOI: | 10.1111/irv.12471 |
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