Postoperative Regression of Retro-odontoid Pseudotumor After Atlantoaxial Posterior Fixation: 11 Years of Experience in Patients With Atlantoaxial Instability.
In: Spine (03622436), Jg. 42 (2017-12-01), Heft 23, S. 1763-1771
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Zugriff:
Study Design: Case series study. Objective: The aim was to investigate the incidence of retro-odontoid pseudotumor in patients with atlantoaxial instability (AAI) and evaluate pseudotumor regression after posterior fixation. Summary Of Background Data: The incidence of retro-odontoid pseudotumor in atlantoaxial instability patients remains uncertain. Moreover, the regression of retro-odontoid pseudotumor after posterior fixation in patients with various underlying diseases needs to be further investigated. Methods: From July 2004 to August 2015, 175 patients with AAI underwent posterior fixation operations at our institution. After excluding 11 patients (previous operation, n = 4; history of tumor, n = 7), the final study population comprised 164 patients. The final study population was categorized according to their underlying diseases (rheumatoid arthritis [RA], os odontoideum, atlanto-occipital assimilation, dens fracture, AAI of unknown cause, etc.) and age (adult and pediatric groups). The incidence of retro-odontoid pseudotumor in each group was analyzed. Pre- and postoperative magnetic resonance or computed tomography images were reviewed to assess its regression following surgery. Results: Of the 164 patients included, 38 had retro-odontoid pseudotumor (23.2%). Three were diagnosed with RA and the rest were non-RA patients including os odontoideum (n = 12), dens fracture (n = 6), atlanto-occipital assimilation (n = 4), Morquio syndrome (n = 1), and AAI of unknown cause (n = 12). Pseudotumor size regressed in all 38 patients after atlantoaxial posterior fixation. There was a statistically significant decrease in pseudotumor size (the length between the anterior border of the odontoid process to the posterior border of the pseudotumor) from a mean length of 17.7 to 14.9 mm (P < 0.001). Conclusions: The patients had various underlying diseases and the overall incidence of retro-odontoid pseudotumor in patients with symptomatic AAI was 23.2% at our institution during the past 11 years. All patients who underwent posterior fixation for AAI showed a statistically significant decrease in pseudotumor size. Level Of Evidence: 4. [ABSTRACT FROM AUTHOR]
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Postoperative Regression of Retro-odontoid Pseudotumor After Atlantoaxial Posterior Fixation: 11 Years of Experience in Patients With Atlantoaxial Instability.
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Autor/in / Beteiligte Person: | Jung Hyun Park ; Lee, Eugene ; Joon Woo Lee ; Kang, Yusuhn ; Joong Mo Ahn ; Yeom, Jin S. ; Heung Sik Kang ; Park, Jung Hyun ; Lee, Joon Woo ; Ahn, Joong Mo ; Kang, Heung Sik |
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Zeitschrift: | Spine (03622436), Jg. 42 (2017-12-01), Heft 23, S. 1763-1771 |
Veröffentlichung: | 2017 |
Medientyp: | academicJournal |
ISSN: | 0362-2436 (print) |
DOI: | 10.1097/BRS.0000000000002222 |
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