Hepatitis C Testing and Patient Characteristics in Washington State's Prisons Between 2012 and 2016.
In: American Journal of Preventive Medicine, Jg. 56 (2019), Heft 1, S. 8-16
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Zugriff:
Introduction: There is no widely accepted testing approach for hepatitis C virus infection in correctional settings, and many U.S. prisons do not provide routine testing. The aim of this study was to determine the most effective hepatitis C virus testing strategy in one U.S. state prison and describe the population with reactive testing. Methods: A retrospective analysis was performed using individuals entering the Washington State prison system, which routinely offers hepatitis C virus testing, to compare routine opt-out with current recommendations for risk-based and one-time testing for individuals born between 1945 and 1965. Additionally, liver fibrosis stage was characterized using aspartate aminotransferase to platelet ratio index and Fibrosis-4 index. Analyses were conducted in 2017. Results: Between 2012 and 2016, a total of 24,567 (83%) individuals were tested for the hepatitis C virus antibody and 4,921 (20%) were reactive (test was positive). There were 2,403 (49%) that had hepatitis C virus RNA testing, with 1,727 (72%) showing chronic infection. Reactive antibody was more prevalent in individuals born between 1945 and 1965 compared with other years (44% vs 17%); however, most cases (72%) were outside of this cohort. Up to 35% of positive reactive tests would be missed with testing targeted by birth cohort and risk behavior. Of chronically infected individuals, 23% had at least moderate liver fibrosis. Conclusions: Targeted testing in the Washington State prison system missed a substantial proportion of hepatitis C virus cases; of those with reactive testing, a sizeable proportion of people had at least moderate liver disease, placing them at risk for complications. Routine testing at entry should be considered by U.S. state prisons. [ABSTRACT FROM AUTHOR]
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Hepatitis C Testing and Patient Characteristics in Washington State's Prisons Between 2012 and 2016.
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Autor/in / Beteiligte Person: | Assoumou, Sabrina A. ; Wang, Jianing ; Tasillo, Abriana ; Eftekhari Yazdi, Golnaz ; Tsui, Judith I. ; Strick, Lara ; Linas, Benjamin P. |
Zeitschrift: | American Journal of Preventive Medicine, Jg. 56 (2019), Heft 1, S. 8-16 |
Veröffentlichung: | 2019 |
Medientyp: | academicJournal |
ISSN: | 0749-3797 (print) |
DOI: | 10.1016/j.amepre.2018.08.016 |
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