COVID-19 vaccination for the prevention and treatment of long COVID: A systematic review and meta-analysis.
In: Brain, Behavior & Immunity, Jg. 111 (2023-07-01), S. 211-229
academicJournal
Zugriff:
• At least one dose of a SARS-CoV-2 vaccine was associated with a protective effect against long COVID. • Long COVID trajectory following vaccination was mixed, with most patients reporting no changes. • Evidence supports SARS-CoV-2 vaccination for the prevention of long COVID. Empirical evidence addressing the association between SARS-CoV-2 vaccination and long COVID would guide public health priorities and inform personal health decisions. Herein, the co-primary objectives are to determine the differential risk of long COVID in vaccinated versus unvaccinated patients, and the trajectory of long COVID following vaccination. Of 2775 articles identified via systematic search, 17 were included, and 6 were meta-analyzed. Meta-analytic results determined that at least one vaccine dose was associated with a protective effect against long COVID (OR 0.539, 95% CI 0.295–0.987, p = 0.045, N = 257 817). Qualitative analysis revealed that trajectories of pre-existing long COVID following vaccination were mixed, with most patients reporting no changes. The evidence herein supports SARS-CoV-2 vaccination for the prevention of long COVID, and recommends long COVID patients adhere to standard SARS-CoV-2 vaccination schedules. [ABSTRACT FROM AUTHOR]
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COVID-19 vaccination for the prevention and treatment of long COVID: A systematic review and meta-analysis.
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Autor/in / Beteiligte Person: | Ceban, Felicia ; Kulzhabayeva, Dana ; Rodrigues, Nelson B. ; Di Vincenzo, Joshua D. ; Gill, Hartej ; Subramaniapillai, Mehala ; Lui, Leanna M.W. ; Cao, Bing ; Mansur, Rodrigo B. ; Ho, Roger C. ; Burke, Matthew J. ; Rhee, Taeho Greg ; Rosenblat, Joshua D. ; McIntyre, Roger S. |
Zeitschrift: | Brain, Behavior & Immunity, Jg. 111 (2023-07-01), S. 211-229 |
Veröffentlichung: | 2023 |
Medientyp: | academicJournal |
ISSN: | 0889-1591 (print) |
DOI: | 10.1016/j.bbi.2023.03.022 |
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