Second Cancer Affecting the Central Nervous System: Systematic Literature Review Exploring the Link Between Malignant Melanoma and Glioblastoma.
In: World Neurosurgery, Jg. 179 (2023-11-01), S. 178-184
academicJournal
Zugriff:
Glioblastoma (GBM) is a malignant primary brain cancer, among the most devastating and lethal diseases of the central nervous system. Similarly, malignant melanoma (MM) is responsible for most skin cancer–related deaths. A link between those 2 aggressive cancers has not yet been established. We present here a systematic review of the literature and an exemplificative case. A systematic review of the literature was conducted to assess possible commonalities between MM and GBM. An exemplificative surgical vignette of a 73-year-old patient with the occurrence of a frontobasal GBM after surgical removal of a metastasis of MM in the same location was then detailed. Fifteen studies published in the English international literature support a link between MM and GBM, both based on epidemiologic and pathophysiologic/genetic aspects. This theory is reinforced by our surgical vignette of a collision tumor with the occurrence of both tumors in the same location several years apart. The evidence reported in the literature, as well as our surgical vignette, support a likely link between the pathogenesis of GBM and MM. [ABSTRACT FROM AUTHOR]
Titel: |
Second Cancer Affecting the Central Nervous System: Systematic Literature Review Exploring the Link Between Malignant Melanoma and Glioblastoma.
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Autor/in / Beteiligte Person: | Todeschi, Julien ; Dannhoff, Guillaume ; Chibbaro, Salvatore ; Segbedji, Felix ; Spatola, Giorgio ; Mallereau, Charles-Henry ; Noel, Georges ; Schott, Roland ; Lhermitte, Benoit ; Cebula, Hélène ; Ganau, Mario |
Zeitschrift: | World Neurosurgery, Jg. 179 (2023-11-01), S. 178-184 |
Veröffentlichung: | 2023 |
Medientyp: | academicJournal |
ISSN: | 1878-8750 (print) |
DOI: | 10.1016/j.wneu.2023.08.073 |
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