Diversity of Upper Respiratory Tract Pathogens in Patients having Flu-Like Symptoms during COVID-19 Pandemic in a Referral Hospital.
In: Journal of Bangladesh College of Physicians & Surgeons, Jg. 41 (2023-10-01), Heft 4, S. 256-261
Online
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Zugriff:
Background: Upper respiratory tract infections (URTIs) are caused by a wide range of viruses and bacteria, however, produce similar symptoms. Routine molecular tests are not performed and empirical use of antibiotics in treating URTIs is a major public health concern. In attempt to unveil the diversity of upper respiratory tract pathogens in the community during COVID-19 pandemic, we have screened 153 nasopharyngeal swab samples from patients having flu like symptoms. Materials and methods: We tested nasopharyngeal swabs by real-time multiplex PCR for 19 viruses and 3 bacteria using cartridge based rapid PCR platform. Results: Of 153 patients sample tested, 103 (67.32%) had a laboratory-confirmed respiratory pathogen. Of the 153 swabs tested rhinovirus/enterovirus was found 25(16.34%), influenza 18(11.77%), RSV 13(8.5%), SARS-CoV2-15(11.11%), other coronaviruses 11(7.19%), parainfluenza 16(10.45%), human metapneumovirus 8(5.23%). Out of 18 influenza cases influenza A was 17(11.12%) and influenza B was 1(0.65%). Among 17 influenza A viruses H1N1pdm09 strain was 9(5.88%), H3 was 5(3.27%). These data shows that even in COVID-19 pandemic period rhinovirus/enterovirus and Influenza dominated over all other respiratory viruses and as a causative agent bacteria might play very insignificant role in URTIs. Conclusion: Our data provides strong evidence against empiric antibiotic use for treating URTIs and highlights a strong need for improving the diagnostic capacity for URTIs by using more molecular testing in the country. [ABSTRACT FROM AUTHOR]
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Diversity of Upper Respiratory Tract Pathogens in Patients having Flu-Like Symptoms during COVID-19 Pandemic in a Referral Hospital.
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Autor/in / Beteiligte Person: | RAHMAN, M. ; AYAZ, K. F. M. ; ISLAM, S. ; HASAN, N. ; RAHIM, R. ; HASAN, A. |
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Zeitschrift: | Journal of Bangladesh College of Physicians & Surgeons, Jg. 41 (2023-10-01), Heft 4, S. 256-261 |
Veröffentlichung: | 2023 |
Medientyp: | academicJournal |
ISSN: | 1015-0870 (print) |
DOI: | 10.3329/jbcps.v41i4.68922 |
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