Precursors of insulin resistance underlying periodontitis in adolescents aged 17–18 years.
In: Oral Diseases, Jg. 29 (2023-11-01), Heft 8, S. 3630-3639
Online
academicJournal
Zugriff:
Objective: To investigate the association between insulin resistance markers and periodontitis in adolescents, analyzing confounder variables and the adiposity as a mediator. Methods: This is population‐based study is representative of adolescents aged 17–18 years from public schools in São Luís, Brazil (n = 405). Insulin resistance was assessed using the Model of Assessment of the Homeostasis of the Insulin Resistance Index (HOMA‐IR) and its percussor triglycerides/HDL‐cholesterol ratio (TG/HDL‐c). The outcome was Initial Periodontitis, a latent variable estimated by the common variance shared among bleeding on probing, probing depth ≥ 4 mm, and clinical attachment loss ≥ 4 mm. The association between insulin resistance and Initial Periodontitis was modeled via pathways triggered by socioeconomic status, smoking, alcohol, and Adiposity, using structural equation modeling. Results: Higher TG/HDL‐c was directly associated with higher Initial Periodontitis (standardized coefficient [SC] = 0.130, p < 0.001). HOMA‐IR was not associated with periodontal outcome (SC = 0.023, p = 0.075), but it was with Adiposity (SC = 0.495, p < 0.001). Higher TG/HDL‐c was associated with Adiposity (SC = 0.202, p < 0.001). Conclusion: The insulin resistance markers were associated with early signs of periodontal breakdown among adolescents, suggesting a possible relationship between diabetes and periodontitis commences early in life. [ABSTRACT FROM AUTHOR]
Titel: |
Precursors of insulin resistance underlying periodontitis in adolescents aged 17–18 years.
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Autor/in / Beteiligte Person: | Ladeira, Lorena L. C. ; Leite, Fábio R. M. ; Nascimento, Gustavo G. ; Saraiva, Maria da Conceição ; Brondani, Mario A. ; Moreira, Ana R. O. ; Ribeiro, Cecilia C. C. |
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Zeitschrift: | Oral Diseases, Jg. 29 (2023-11-01), Heft 8, S. 3630-3639 |
Veröffentlichung: | 2023 |
Medientyp: | academicJournal |
ISSN: | 1354-523X (print) |
DOI: | 10.1111/odi.14283 |
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