Cost Effectiveness of Management of Mild-to-Moderate Atopic Dermatitis with 1% Pimecrolimus Cream in Children and Adolescents 2–17 Years of Age.
In: American Journal of Clinical Dermatology, Jg. 7 (2006-03-01), Heft 2, S. 133-139
Online
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Zugriff:
INTRODUCTION: Atopic dermatitis (AD) has the potential to cause a long-term economic impact on patients, their families, and the healthcare system. OBJECTIVE: To determine if 1% pimecrolimus cream is cost-effective in treating mild-to-moderate AD in patients 2–17 years of age. METHODS: Data on the efficacy of AD management with 1% pimecrolimus cream (Elidel, Novartis Pharma GmbH, Wehr, Germany) were obtained from a 12-month, randomized, double-blind, multinational, controlled clinical trial comparing pimecrolimus and conventional therapy. Markov modeling was used for the economic model, based on: (i) Investigator’s Global Assessment scores assessed at each visit during the clinical trial; (ii) estimated costs for medication and physician visits for each level of disease severity; and (iii) utility values for each level of disease severity. The perspective was that of a third-party payer. RESULTS: In 2004 US dollars, the incremental cost-effectiveness of 1% pimecrolimus cream was $US38 231 per quality-adjusted life year (QALY) gained compared with conventional therapy. Sensitivity analyses showed a range of $US27 299 to $US63 457 per QALY gained. CONCLUSION: With an incremental cost-effectiveness ratio of <$US50 000 per QALY gained, 1% pimecrolimus cream offers a cost-effective therapeutic option in the management of AD. [ABSTRACT FROM AUTHOR]
Titel: |
Cost Effectiveness of Management of Mild-to-Moderate Atopic Dermatitis with 1% Pimecrolimus Cream in Children and Adolescents 2–17 Years of Age.
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Autor/in / Beteiligte Person: | Ellis, Charles N. ; Kahler, Kristijan H. ; Grueger, Jens ; Chang, Jane |
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Zeitschrift: | American Journal of Clinical Dermatology, Jg. 7 (2006-03-01), Heft 2, S. 133-139 |
Veröffentlichung: | 2006 |
Medientyp: | academicJournal |
ISSN: | 1175-0561 (print) |
DOI: | 10.2165/00128071-200607020-00006 |
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