Efectos metabólicos de Lepidium meyenii Walpers, "MACA" y Lupinus mutabilis Sweet, "CHOCHO" en ratas.

Lepidium meyenii, "Maca" and the Lupinus mutabilis S, "Chocho" belong to the group of plants known as nutraceutic plants. Maca has been used since the seventh century BC and it was the most important crop in Peruvian agriculture during the sisxteenth century, around the time when the Spanierds arrived to our territory. This plant belongs to the Cruciferaceae (Brasicaceae) family. Both plants (Maca and Chocho) were used in Peru, since pre Columbian times as part of the diet as well as for their medicinal properties. In these issue, we evaluated the effects of Maca and Lupinus on female Sprague Dawley rats (weight between 120 and 170 g), and we tested Hemoglobin, hematocrit, total proteins, albumin, TOO, TOP and corporal weight values after 15 and 30 days of trestment. We used 60 albino rats, distributed in three groups of twenty animals each one. The first group was the control and received 0,9% saline solution for 30 days. The second group received Maca flour watery solution at 500 mg/kg doses and the third group received Lupinus, watery solution at 500 mg/kg doses for thirty days. Our results showed an increase of the serum levels of triglycerides due to Lupinus (from 45.9 to 76.55mg) after 30 days in relation to the control that varied from 43.5 to 61.8mg. With Maca variations were from 43.5 to 56.7 mg. We also appeciated a slight increase of hematocrit and haemoglobin after 15 days of treatment with Maca in relation to the control group. Analyses between control and treated groups showed no statistical differences. [ABSTRACT FROM AUTHOR]

El Lepidiurn meyenii, "Maca" y el Lupinus Mutabilis S, "Chocho", pertenecen al grupo de plantas conocidas como nutracéticas. El uso de la Maca se remonta al siglo 7 AC. En la época de la conquista fue el producto más importante del agro peruano; pertenece a la familia de las Cruciferaceae (Brasicaceae). Ambas plantas son usadas, desde tiempos precolombinos, como medicinales y/o alimenticias. En el presente trabajo, evaluamos el efecto de Maca y de Lupinus, en ratas hembras Sprague Dawley, con peso corporal entre 120 y 170g, sobre los valores de hematocrito, hemoglobina, glucosa, colesterol, triglicéridos, HDL, LDL, proteínas totales, albümina, TOO, TOP y peso corporal, después de 15 y 30 días de tratamiento. Utilizamos 60 ratas albinas distribuidas en 3 grupos de 20 animales cada uno. Al primer grupo se le administró, por 30 días, suero fisiológico (GRUPO CONTROL). Al segundo grupo se le administró cocimiento acuoso de harina de maca, a Ia dosis de 500 mg/Kg, y al tercer grupo, cocimiento acuoso de harina de semillas de chocho, desamargado y descascarado, a las dosis de 500 mg/Kg, durante 30 días. Nuestros resultados, indican un aumento de los niveles de triglicéridos en sangre, por efecto de Lupinus (de 45.9 a 76.55 mg), a los 30 días, con respecto a! control, que varió de 43.5 a 61.8 mg. Con maca, las variaciones fueron de 43,5 a 56.7 mg: asimismo, apreciamos un ligero aumento del hematocrito y la hemoglobina, a los 15 días de tratamiento, con maca. Los análisis estadisticos entre el grupo control y los tratados, con Maca y Lupinus, no fueron significativos. [ABSTRACT FROM AUTHOR]