Muco-cutaneous manifestations in 178 renal transplant recipients.
In: Clinical Transplantation, Jg. 25 (2011-05-01), Heft 3, S. 395-400
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academicJournal
Zugriff:
Khosravi M, Golchai J, Mokhtari G. Muco-cutaneous manifestations in 178 renal transplant recipients. Clin Transplant 2011: 25: 395-400. © 2010 John Wiley & Sons A/S. Mucosal membrane and skin can be affected by immunosuppressive drug(s) and immunosuppression itself. The spectrum of muco-cutaneous lesions can range from malignancy at one end to infection, iatrogenic lesions, and esthetic effects on the other end. In Razi Hospital of Guilan University of Medical Sciences, a cross-sectional study for the detection of muco-cutaneous lesions in 178 renal transplant recipients (RTRs) was conducted from the years 2001 to 2006. Biopsy and skin scraping according to the type of skin lesions were performed. A total of 31 RTRs (25%) had normal skin. Iatrogenic lesions were the most common (70%) followed by infectious lesions (57%), and miscellaneous skin lesions were exhibited by 26% of the patients. Among the iatrogenic skin lesions, gingival hyperplasia was the most common lesion (48%), followed by hypertrichosis and acne. Malignant lesions (biopsy proven) were recorded in seven patients (5%). Four patients were found to have Kaposi's sarcoma, and three patients were identified with basal cell carcinoma. Our results showed that muco-cutaneous lesions are crucial problems with RTRs. Attending physicians must pay close attention to skin care regularly and consider reduction of immunosuppression to a safe level, and patient must have self-checkups. [ABSTRACT FROM AUTHOR]
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Muco-cutaneous manifestations in 178 renal transplant recipients.
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Autor/in / Beteiligte Person: | Khosravi, Masoud ; Golchai, Javad ; Mokhtari, Gholamreza |
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Zeitschrift: | Clinical Transplantation, Jg. 25 (2011-05-01), Heft 3, S. 395-400 |
Veröffentlichung: | 2011 |
Medientyp: | academicJournal |
ISSN: | 0902-0063 (print) |
DOI: | 10.1111/j.1399-0012.2010.01284.x |
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