In vivo quantitative three-dimensional motion mapping of the murine myocardium with PC-MRI at 17.6 T.
In: Magnetic resonance in medicine, Jg. 55 (2006-05-01), Heft 5, S. 1058-64
Online
academicJournal
Zugriff:
This work presents a method that allows for the assessment of 3D murine myocardial motion in vivo at microscopic resolution. Phase-contrast (PC) magnetic resonance imaging (MRI) at 17.6 T was applied to map myocardial motion in healthy mice along three gradient directions. High-resolution velocity maps were acquired at three different levels in the murine myocardium with an in-plane resolution of 98 mum, a slice thickness of 0.6 mm, and a temporal resolution of 6 ms. The applied PC-MRI method was validated with phantom experiments that confirmed the correctness of the method with deviations of <1.7%. Myocardial in-plane velocities between 0.5 cm/s and 2.2 cm/s were determined for the healthy murine myocardium. Through-plane velocities of 0.1-0.83 cm/s were measured. Velocity data was also used to calculate the myocardial twist angle during systole at different slices in the short-axis view.
(Copyright (c) 2006 Wiley-Liss, Inc.)
Titel: |
In vivo quantitative three-dimensional motion mapping of the murine myocardium with PC-MRI at 17.6 T.
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Autor/in / Beteiligte Person: | Herold, V ; Mörchel, P ; Faber, C ; Rommel, E ; Haase, A ; Jakob, PM |
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Zeitschrift: | Magnetic resonance in medicine, Jg. 55 (2006-05-01), Heft 5, S. 1058-64 |
Veröffentlichung: | 1999- : New York, NY : Wiley ; <i>Original Publication</i>: San Diego : Academic Press,, 2006 |
Medientyp: | academicJournal |
ISSN: | 0740-3194 (print) |
DOI: | 10.1002/mrm.20866 |
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