Zum Hauptinhalt springen
Hochschulbibliothek der Hochschule Düsseldorf

Trauma and Stem Cells: Biology and Potential Therapeutic Implications.

Thurairajah, K ; Broadhead, ML ; et al.
In: International journal of molecular sciences, Jg. 18 (2017-03-07), Heft 3
Online academicJournal
Zugriff:
Full Text Finder (Volltext)

Trauma may cause irreversible tissue damage and loss of function despite current best practice. Healing is dependent both on the nature of the injury and the intrinsic biological capacity of those tissues for healing. Preclinical research has highlighted stem cell therapy as a potential avenue for improving outcomes for injuries with poor healing capacity. Additionally, trauma activates the immune system and alters stem cell behaviour. This paper reviews the current literature on stem cells and its relevance to trauma care. Emphasis is placed on understanding how stem cells respond to trauma and pertinent mechanisms that can be utilised to promote tissue healing. Research involving notable difficulties in trauma care such as fracture non-union, cartilage damage and trauma induced inflammation is discussed further.

Titel:
Trauma and Stem Cells: Biology and Potential Therapeutic Implications.
Autor/in / Beteiligte Person: Thurairajah, K ; Broadhead, ML ; Balogh, ZJ
Link:
Zeitschrift: International journal of molecular sciences, Jg. 18 (2017-03-07), Heft 3
Veröffentlichung: Basel, Switzerland : MDPI, [2000-, 2017
Medientyp: academicJournal
ISSN: 1422-0067 (electronic)
DOI: 10.3390/ijms18030577
Schlagwort:
  • Animals
  • Cell Differentiation
  • Humans
  • Inflammation etiology
  • Multiple Organ Failure etiology
  • Muscles pathology
  • Muscles physiology
  • Neovascularization, Physiologic
  • Regeneration
  • Stem Cell Research
  • Wounds and Injuries pathology
  • Wounds and Injuries therapy
  • Stem Cells cytology
  • Stem Cells physiology
  • Wound Healing physiology
  • Wounds and Injuries etiology
Sonstiges:
  • Nachgewiesen in: MEDLINE
  • Sprachen: English
  • Publication Type: Journal Article; Review
  • Language: English
  • [Int J Mol Sci] 2017 Mar 07; Vol. 18 (3). <i>Date of Electronic Publication: </i>2017 Mar 07.
  • MeSH Terms: Stem Cells / *cytology ; Stem Cells / *physiology ; Wound Healing / *physiology ; Wounds and Injuries / *etiology ; Animals ; Cell Differentiation ; Humans ; Inflammation / etiology ; Multiple Organ Failure / etiology ; Muscles / pathology ; Muscles / physiology ; Neovascularization, Physiologic ; Regeneration ; Stem Cell Research ; Wounds and Injuries / pathology ; Wounds and Injuries / therapy
  • References: Circulation. 2004 Mar 16;109(10):1292-8. (PMID: 14993122) ; Mol Ther. 2013 Aug;21(8):1631-8. (PMID: 23732992) ; Australas Emerg Nurs J. 2012 Feb;15(1):45-54. (PMID: 22813623) ; Stem Cells Transl Med. 2012 Feb;1(2):142-9. (PMID: 23197761) ; Cell Mol Life Sci. 2015 May;72(9):1663-77. (PMID: 25572293) ; Wound Repair Regen. 2009 Mar-Apr;17(2):185-91. (PMID: 19320886) ; J Bone Joint Surg Am. 2002 May;84-A(5):822-32. (PMID: 12004029) ; J Mol Cell Cardiol. 2005 Nov;39(5):733-42. (PMID: 16199052) ; Wound Repair Regen. 2013 Sep-Oct;21(5):746-54. (PMID: 23937682) ; Exp Cell Res. 2010 Oct 1;316(16):2676-82. (PMID: 20553713) ; Circulation. 2004 Jul 20;110(3):349-55. (PMID: 15238461) ; Injury. 2009 Jan;40(1):99-103. (PMID: 19117562) ; Transplantation. 2014 Jun 15;97(11):e66-8. (PMID: 24887752) ; Am J Pathol. 2006 Oct;169(4):1440-57. (PMID: 17003498) ; J Trauma Acute Care Surg. 2013 Feb;74(2):508-15. (PMID: 23147181) ; J Orthop Res. 2010 Aug;28(8):1007-14. (PMID: 20135674) ; PLoS One. 2010 Apr 26;5(4):e10088. (PMID: 20436665) ; Stem Cells Int. 2015;2015:831095. (PMID: 26106431) ; Am J Pathol. 2006 Aug;169(2):719-28. (PMID: 16877369) ; Nat Biotechnol. 2014 Mar;32(3):252-60. (PMID: 24561556) ; Stem Cells. 2015 May;33(5):1501-11. (PMID: 25594525) ; Expert Opin Biol Ther. 2016;16(4):535-57. (PMID: 26798997) ; J Bone Joint Surg Am. 2014 Jan 15;96(2):90-8. (PMID: 24430407) ; J Neurotrauma. 2007 Apr;24(4):625-37. (PMID: 17439346) ; Circulation. 2005 Mar 8;111(9):1114-20. (PMID: 15723985) ; Gend Med. 2012 Apr;9(2):129-36. (PMID: 22361839) ; Cell Transplant. 2013;22(8):1395-408. (PMID: 22889498) ; J Craniofac Surg. 2013 May;24(3):830-3. (PMID: 23714890) ; Nature. 2010 Jun 10;465(7299):704-12. (PMID: 20535199) ; Science. 1997 Feb 14;275(5302):964-7. (PMID: 9020076) ; Biomed Res Int. 2013;2013:561098. (PMID: 24381939) ; Annu Rev Cell Dev Biol. 2005;21:605-31. (PMID: 16212509) ; Acta Pharmacol Sin. 2013 Jun;34(6):747-54. (PMID: 23736003) ; Keio J Med. 2005 Sep;54(3):132-41. (PMID: 16237275) ; J Tissue Eng Regen Med. 2015 Mar;9(3):224-35. (PMID: 23038677) ; J Tissue Eng Regen Med. 2012 Dec;6 Suppl 3:s60-7. (PMID: 22761111) ; J Biol Chem. 2011 Jul 22;286(29):26016-27. (PMID: 21566131) ; An Bras Dermatol. 2014 Mar-Apr;89(2):286-91. (PMID: 24770506) ; J Hypertens. 2009 Jun;27(6):1202-16. (PMID: 19307985) ; Crit Care. 2009;13(4):R118. (PMID: 19604356) ; Blood. 1998 Jul 15;92(2):362-7. (PMID: 9657732) ; Cytotherapy. 2013 Sep;15(9):1136-47. (PMID: 23831362) ; Osteoarthritis Cartilage. 2011 Sep;19(9):1081-90. (PMID: 21624477) ; Ann Surg. 2003 Nov;238(5):748-53. (PMID: 14578739) ; J Biol Chem. 2003 Apr 11;278(15):12601-4. (PMID: 12556454) ; Connect Tissue Res. 2012;53(2):149-59. (PMID: 22149641) ; J Trauma. 2003 Jul;55(1):7-13. (PMID: 12855874) ; Nat Rev Immunol. 2006 Feb;6(2):93-106. (PMID: 16491134) ; Int Wound J. 2015 Feb;12(1):10-6. (PMID: 23490259) ; Biochem Biophys Res Commun. 2014 May 30;448(2):212-7. (PMID: 24780395) ; Br J Sports Med. 2006 Aug;40(8):719-22. (PMID: 16807304) ; J Orthop Res. 2011 Apr;29(4):516-22. (PMID: 21337391) ; Stem Cells. 2006 Apr;24(4):1030-41. (PMID: 16253981) ; Cell. 2000 Jan 7;100(1):157-68. (PMID: 10647940) ; J Surg Res. 2015 Dec;199(2):615-21. (PMID: 26193832) ; Anesthesiology. 2015 Feb;122(2):363-73. (PMID: 25490744) ; Crit Care Med. 2013 Nov;41(11):e319-33. (PMID: 23760104) ; Stem Cells. 2009 Aug;27(8):1887-98. (PMID: 19544445) ; J Bone Miner Metab. 1999;17(3):171-7. (PMID: 10757676) ; Indian J Plast Surg. 2012 May;45(2):229-36. (PMID: 23162221) ; Ann Biomed Eng. 2010 May;38(5):1767-79. (PMID: 20217480) ; Nat Immunol. 2002 Jul;3(7):687-94. (PMID: 12068293) ; Stem Cells. 2010 May;28(5):965-73. (PMID: 20333749) ; Proc Natl Acad Sci U S A. 1992 Apr 1;89(7):2804-8. (PMID: 1372992) ; Transfusion. 2009 Dec;49(12):2652-60. (PMID: 19682336) ; Injury. 2010 Nov;41 Suppl 2:S94-8. (PMID: 21144938) ; Stem Cell Res Ther. 2011 Mar 14;2(2):13. (PMID: 21418553) ; Gerontology. 2016;62(2):216-25. (PMID: 26045256) ; Bone. 2015 Jan;70:19-27. (PMID: 25263520) ; Stem Cell Res Ther. 2016 Mar 09;7:37. (PMID: 26960535) ; Nature. 2006 Jun 29;441(7097):1061-7. (PMID: 16810240) ; Shock. 2011 Sep;36(3):216-22. (PMID: 21610569) ; Cytotherapy. 2013 Jul;15(7):840-9. (PMID: 23623275) ; J Dermatol Sci. 2007 Oct;48(1):15-24. (PMID: 17643966) ; Blood. 2007 Feb 15;109(4):1422-32. (PMID: 17038530) ; J Biol Chem. 1992 Jun 5;267(16):10931-4. (PMID: 1375931) ; J Trauma. 2008 Aug;65(2):349-53. (PMID: 18695470) ; Stem Cells Transl Med. 2014 Jan;3(1):128-34. (PMID: 24307697) ; PLoS One. 2014 May 14;9(5):e97369. (PMID: 24826895) ; FEBS J. 2013 Sep;280(17):4036-50. (PMID: 23735050) ; Lancet Respir Med. 2015 Jan;3(1):24-32. (PMID: 25529339) ; J Trauma. 1999 Sep;47(3 Suppl):S46-55. (PMID: 10496611) ; Am J Pathol. 2004 Mar;164(3):1007-19. (PMID: 14982854) ; Sci Rep. 2016 Mar 17;6:23076. (PMID: 26983696) ; Med J Aust. 2008 Nov 17;189(10):546-50. (PMID: 19012550) ; Stem Cells Dev. 2007 Feb;16(1):119-29. (PMID: 17348810) ; Wound Repair Regen. 2015 Mar-Apr;23(2):262-7. (PMID: 25754793) ; Arthroscopy. 2013 Apr;29(4):684-94. (PMID: 23380230) ; Tissue Eng Part C Methods. 2014 Jun;20(6):524-32. (PMID: 24147916) ; Cells Tissues Organs. 2001;169(1):12-20. (PMID: 11340257) ; Nat Med. 2012 Apr 15;18(5):759-65. (PMID: 22504485) ; Cell. 2007 Jun 1;129(5):999-1010. (PMID: 17540178) ; J Trauma Acute Care Surg. 2015 Oct;79(4):602-8. (PMID: 26402534) ; J Clin Pathol. 2002 Sep;55(9):693-8. (PMID: 12195001) ; Arthritis Rheum. 2011 May;63(5):1289-300. (PMID: 21538315) ; J Trauma Acute Care Surg. 2015 Feb;78(2):282-8. (PMID: 25602756) ; Ann Biomed Eng. 2009 Mar;37(3):492-502. (PMID: 19125331) ; J Bone Joint Surg Am. 2013 Jul 17;95(14):1278-88. (PMID: 23864176) ; Nat Med. 2009 Jan;15(1):42-9. (PMID: 19098906) ; Stem Cells Int. 2010 Dec 16;2010:519028. (PMID: 21234334) ; Stem Cells. 2007 Oct;25(10):2648-59. (PMID: 17615264) ; Tissue Eng Part A. 2014 Nov;20(21-22):3050-62. (PMID: 24785365) ; BMC Musculoskelet Disord. 2016 May 26;17:230. (PMID: 27229856) ; Stem Cells Int. 2016;2016:6289825. (PMID: 27340408) ; Am J Pathol. 2002 Sep;161(3):895-907. (PMID: 12213718) ; Blood. 2007 Oct 1;110(7):2440-8. (PMID: 17536014) ; Wound Repair Regen. 2015 Jan-Feb;23(1):115-23. (PMID: 25571903) ; Wound Repair Regen. 2016 Jan-Feb;24(1):127-35. (PMID: 26663663) ; Cell Tissue Res. 2012 Jun;348(3):371-7. (PMID: 22447168) ; Tissue Eng Part A. 2014 May;20(9-10):1392-402. (PMID: 24367947) ; J Biol Chem. 2014 Apr 11;289(15):10330-44. (PMID: 24550383) ; Cell Prolif. 2007 Oct;40(5):671-84. (PMID: 17877609) ; J Am Coll Surg. 2013 Jan;216(1):57-64. (PMID: 23063381) ; J Biophys Biochem Cytol. 1961 Feb;9:493-5. (PMID: 13768451) ; Regen Med. 2012 Nov;7(6):833-50. (PMID: 23164083) ; Rejuvenation Res. 2011 Feb;14(1):57-66. (PMID: 21329452) ; Circ Res. 2000 Oct 27;87(9):728-30. (PMID: 11055974) ; J Sex Med. 2012 Aug;9(8):1988-2000. (PMID: 22759755) ; Stem Cells Cloning. 2015 Aug 28;8:117-24. (PMID: 26357483) ; Front Biosci (Landmark Ed). 2011 Jun 01;16:2271-88. (PMID: 21622176)
  • Contributed Indexing: Keywords: DAMP; healing; inflammation; stem cells; trauma
  • Entry Date(s): Date Created: 20170309 Date Completed: 20170428 Latest Revision: 20181113
  • Update Code: 20240513
  • PubMed Central ID: PMC5372593

Klicken Sie ein Format an und speichern Sie dann die Daten oder geben Sie eine Empfänger-Adresse ein und lassen Sie sich per Email zusenden.

oder
oder

Wählen Sie das für Sie passende Zitationsformat und kopieren Sie es dann in die Zwischenablage, lassen es sich per Mail zusenden oder speichern es als PDF-Datei.

oder
oder

Bitte prüfen Sie, ob die Zitation formal korrekt ist, bevor Sie sie in einer Arbeit verwenden. Benutzen Sie gegebenenfalls den "Exportieren"-Dialog, wenn Sie ein Literaturverwaltungsprogramm verwenden und die Zitat-Angaben selbst formatieren wollen.

xs 0 - 576
sm 576 - 768
md 768 - 992
lg 992 - 1200
xl 1200 - 1366
xxl 1366 -