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Objective: The objective of the study was to know the profile of patients diagnosed with chronic obstructive pulmonary disease (COPD) and who have never been smokers.

Design: A transversal study.

Location: Primary Care Centre of Pla d'Urgell (Primary care setting in Lleida, Spain).

Participants: 512 patients older than 40 years with COPD from Primary Care Centre of Pla d'Urgell with a compatible spirometry [forced expiratory volume in one second (FEV 1 )/forced vital capacity (FVC) ratio <0.7) to the beginning of the study.

Main Measurements: The dependent variable was de COPD in non-smokers and the independents were variables collected from the information on the respiratory clinical history, the risk factors of the patients and on quality of life. We designed a predictor model of COPD in non-smokers compared to smokers.

Results: 33.2% of COPD patients had never been smokers, 59.4% of whom were women. The average FEV 1 for non-smokers was 70.5 (SD=17.1), higher than 62.6 (SD=18.5) for smokers/former smokers (p<0.001). The coverage of pneumococcal vaccination 23V was better in non-smokers (75.3%), p<0.001. COPD in non-smokers (compared to smokers/former smokers) were: mostly women (OR=16.46), older (OR=1.1), with better FEV 1 (OR=1.1), better perception of quality, EuroQoL-5D (OR=0.8), with lower prevalence of diabetes (OR=0.5), lower level of studies (OR=0.2), and with fewer previous hospitalizations (OR=0.3).

Conclusions: The study evidences a high proportion of non-smokers in COPD patients. Our study aims that older women with less severity would be associated with an increased risk of COPD in non-smokers. It seems to indicate that COPD in non-smokers would appear at later ages and would be milder than smoking-related COPD.

Titel:	[Prevalence and characteristics of chronic obstructive pulmonary disease in non-smokers].
Autor/in / Beteiligte Person:	Montserrat-Capdevila, J ; Godoy, P ; Marsal, JR ; Ortega, M ; Barbé, F ; Castañ, MT ; Seminario, MA ; Pujol, J ; Alsedà, M
Link:	Full Text Finder (Volltext)
Zeitschrift:	Atencion primaria, Jg. 51 (2019-12-01), Heft 10, S. 602-609
Veröffentlichung:	Madrid : Elsevier España ; <i>Original Publication</i>: Barcelona : Haymarket,, 2019
Medientyp:	academicJournal
ISSN:	1578-1275 (electronic)
DOI:	10.1016/j.aprim.2017.10.012
Schlagwort:	Adult Age Factors Aged Cross-Sectional Studies Ex-Smokers Female Forced Expiratory Volume Humans Male Middle Aged Prevalence Pulmonary Disease, Chronic Obstructive physiopathology Sex Distribution Spain epidemiology Spirometry Vital Capacity Non-Smokers statistics & numerical data Pulmonary Disease, Chronic Obstructive epidemiology
Sonstiges:	Nachgewiesen in: MEDLINE Sprachen: Spanish; Castilian Transliterated Title: Prevalencia y características de la enfermedad pulmonar obstructiva crónica en no fumadores. Publication Type: Journal Article Language: Spanish; Castilian [Aten Primaria] 2019 Dec; Vol. 51 (10), pp. 602-609. <i>Date of Electronic Publication: </i>2018 Nov 16. MeSH Terms: Non-Smokers / statistics & numerical data ; Pulmonary Disease, Chronic Obstructive / epidemiology ; Adult ; Age Factors ; Aged ; Cross-Sectional Studies ; Ex-Smokers ; Female ; Forced Expiratory Volume ; Humans ; Male ; Middle Aged ; Prevalence ; Pulmonary Disease, Chronic Obstructive / physiopathology ; Sex Distribution ; Spain / epidemiology ; Spirometry ; Vital Capacity Comments: Comment in: Aten Primaria. 2019 Nov;51(9):591. (PMID: 31151819) ; Comment in: Aten Primaria. 2019 Nov;51(9):589-590. (PMID: 31230850) References: Chest. 2011 Apr;139(4):752-763. (PMID: 20884729) ; Eur Respir J Suppl. 2003 Nov;46:76s-80s. (PMID: 14621109) ; Am J Public Health. 1995 May;85(5):702-6. (PMID: 7733432) ; Proc Natl Acad Sci U S A. 2000 Nov 21;97(24):13286-93. (PMID: 11087870) ; Lancet. 2009 Aug 29;374(9691):733-43. (PMID: 19716966) ; Environ Res. 2005 Sep;99(1):93-8. (PMID: 16053933) ; Respir Res. 2006 May 02;7:70. (PMID: 16669999) ; Respir Med. 2009 May;103(5):692-9. (PMID: 19131231) ; Thorax. 1999 Jul;54(7):581-6. (PMID: 10377201) ; Aten Primaria. 2015 Oct;47(8):498-504. (PMID: 25778409) ; Am J Respir Crit Care Med. 2017 Nov 1;196(9):1152-1161. (PMID: 28489427) ; Chest. 2014 Jun;145(6):1298-1304. (PMID: 24356778) ; Eur Respir J. 2010 Dec;36(6):1259-69. (PMID: 20413537) ; Int J Epidemiol. 2001 Jun;30(3):540-6. (PMID: 11416080) ; Am J Respir Crit Care Med. 2007 Sep 15;176(6):532-55. (PMID: 17507545) ; Respir Med. 2003 Feb;97(2):115-22. (PMID: 12587960) ; BMJ Open. 2014 Dec 18;4(12):e006171. (PMID: 25524545) ; Arch Bronconeumol. 2017 Feb;53(2):45-46. (PMID: 27646821) ; Eur Respir J. 2009 Mar;33(3):509-18. (PMID: 19251797) ; BMC Fam Pract. 2015 Dec 08;16:173. (PMID: 26642879) ; Respir Med. 2015 Nov;109(11):1439-45. (PMID: 26440676) ; Diabet Med. 2002 Feb;19(2):167-70. (PMID: 11874435) ; Arch Bronconeumol. 2009;45 Suppl 4:42-6. (PMID: 20116749) ; Am J Respir Crit Care Med. 2002 Oct 15;166(8):1078-83. (PMID: 12379551) ; J Clin Epidemiol. 2000 Jul;53(7):755-61. (PMID: 10941954) ; N Engl J Med. 2003 May 1;348(18):1747-55. (PMID: 12724480) ; Respir Med. 2005 Aug;99(8):985-95. (PMID: 15950139) ; Thorax. 2006 Dec;61(12):1043-7. (PMID: 17040932) ; Chest. 2000 Oct;118(4):981-9. (PMID: 11035667) ; Int J Tuberc Lung Dis. 2016 Mar;20(3):389-95. (PMID: 27046722) ; PLoS One. 2016 Mar 24;11(3):e0151981. (PMID: 27010214) ; Eur Respir J. 2009 Sep;34(3):648-54. (PMID: 19720809) ; Eur Respir J. 2006 Mar;27(3):542-6. (PMID: 16507854) ; Psychol Med. 2006 Jan;36(1):27-36. (PMID: 16202189) ; Lancet. 2001 Aug 25;358(9282):619-24. (PMID: 11530148) ; Am J Med. 2005 Dec;118(12):1364-72. (PMID: 16378780) Contributed Indexing: Keywords: Chronic obstructive pulmonary disease; Enfermedad pulmonar obstructiva crónica; Factores de riesgo; Fumadores; No fumadores; Non-smokers; Risk factors; Smokers Entry Date(s): Date Created: 20181121 Date Completed: 20200914 Latest Revision: 20200914 Update Code: 20231215 PubMed Central ID: PMC6930941

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[Prevalence and characteristics of chronic obstructive pulmonary disease in non-smokers].