The impact of a randomized dietary and physical activity intervention on chronic inflammation among obese African-American women.
In: Women & health, Jg. 60 (2020-08-01), Heft 7, S. 792-805
academicJournal
Zugriff:
Lifestyle interventions may reduce inflammation and lower breast cancer (BrCa) risk. This randomized trial assessed the impact of the Sistas Inspiring Sistas Through Activity and Support (SISTAS) study on plasma C-reactive protein (CRP), interleukin-6 (IL-6) and Dietary Inflammatory Index (DII). This unblinded, dietary and physical activity trial was implemented in 337 obese (body mass index [BMI] ≥30 kg/m 2 ) African American (AA) women recruited between 2011 and 2015 in South Carolina through a community-based participatory approach with measurements at baseline, 3 months, and 12 months. Participants were randomized into either intervention (n = 176) or wait-list control group (n = 161). Linear mixed-effect models were used for analyses of CRP and IL-6. Baseline CRP was significantly higher in those with greater obesity, body fat percentage, and waist circumference (all p <.01). No difference was observed between groups for CRP or IL-6 at 3 or 12 months; however, improvements in diet were observed in the intervention group compared to the control group ( p = .02) at 3 months but were not sustained at 12 months. Although the intervention was not successful at reducing levels of CRP or IL-6, a significant decrease was observed in DII score for the intervention group, indicating short-term positive dietary change.
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The impact of a randomized dietary and physical activity intervention on chronic inflammation among obese African-American women.
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Autor/in / Beteiligte Person: | Babatunde, OA ; Arp Adams, S ; Truman, S ; Sercy E, MSPH ; Murphy, AE ; Khan S, MSW ; Hurley TG, MS ; Wirth, MD ; Choi, SK ; Johnson H, BA ; Hebert JR ScD |
Zeitschrift: | Women & health, Jg. 60 (2020-08-01), Heft 7, S. 792-805 |
Veröffentlichung: | Philadelphia : Routledge ; <i>Original Publication</i>: Old Westbury, N. Y., Biological Sciences Program, State Univ. of New York, College at Old Westbury., 2020 |
Medientyp: | academicJournal |
ISSN: | 1541-0331 (electronic) |
DOI: | 10.1080/03630242.2020.1746950 |
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