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Overweight and obesity are key risk factors of cardiovascular disease (CVD). Obesity is currently presented as a pro-inflammatory state with an expansion in the outflow of inflammatory cytokines, such as interleukin-6 (IL-6) and tumor necrosis factor-alpha (TNF-α), alongside the expanded emission of leptin. The present review aimed to evaluate the relationship between obesity and inflammation and their impacts on the development of cardiovascular disease. A literature search was conducted by employing three academic databases, namely PubMed (Medline), Scopus (EMBASE), and the Cumulative Index to Nursing and Allied Health Literature (CINAHL). The search presented 786 items, and by inclusion and exclusion filterers, 59 works were considered for final review. The Newcastle-Ottawa Scale (NOS) method was adopted to conduct quality assessment; 19 papers were further selected based on the quality score. Obesity-related inflammation leads to a low-grade inflammatory state in organisms by upregulating pro-inflammatory markers and downregulating anti-inflammatory cytokines, thereby contributing to cardiovascular disease pathogenesis. Because of inflammatory and infectious symptoms, adipocytes appear to instigate articulation and discharge a few intense stage reactants and carriers of inflammation. Obesity and inflammatory markers are strongly associated, and are important factors in the development of CVD. Hence, weight management can help prevent cardiovascular risks and poor outcomes by inhibiting inflammatory mechanisms.

Competing Interests: No authors have any conflicts of interest during the publication of the manuscript.

Titel:	Impact of Obesity-Induced Inflammation on Cardiovascular Diseases (CVD).
Autor/in / Beteiligte Person:	Battineni, G ; Sagaro, GG ; Chintalapudi, N ; Amenta, F ; Tomassoni, D ; Tayebati, SK
Link:	Full Text Finder (Volltext)
Zeitschrift:	International journal of molecular sciences, Jg. 22 (2021-04-30), Heft 9
Veröffentlichung:	Basel, Switzerland : MDPI, [2000-, 2021
Medientyp:	academicJournal
ISSN:	1422-0067 (electronic)
DOI:	10.3390/ijms22094798
Schlagwort:	Adipocytes metabolism Adipocytes pathology Animals Cardiovascular Diseases metabolism Cardiovascular Diseases pathology Cytokines analysis Cytokines metabolism Humans Inflammation metabolism Inflammation pathology Obesity metabolism Obesity pathology Cardiovascular Diseases etiology Inflammation complications Obesity complications
Sonstiges:	Nachgewiesen in: MEDLINE Sprachen: English Publication Type: Journal Article; Meta-Analysis; Systematic Review Language: English [Int J Mol Sci] 2021 Apr 30; Vol. 22 (9). <i>Date of Electronic Publication: </i>2021 Apr 30. MeSH Terms: Cardiovascular Diseases / etiology ; Inflammation / complications ; Obesity / *complications ; Adipocytes / metabolism ; Adipocytes / pathology ; Animals ; Cardiovascular Diseases / metabolism ; Cardiovascular Diseases / pathology ; Cytokines / analysis ; Cytokines / metabolism ; Humans ; Inflammation / metabolism ; Inflammation / pathology ; Obesity / metabolism ; Obesity / pathology References: J Affect Disord. 2019 Jan 15;243:83-95. (PMID: 30236762) ; N Engl J Med. 2002 Aug 1;347(5):305-13. (PMID: 12151467) ; J Neurol Neurosurg Psychiatry. 2016 Apr;87(4):356-62. (PMID: 25918047) ; Circulation. 1996 Dec 1;94(11):2850-5. (PMID: 8941112) ; Psychiatr Clin North Am. 2011 Dec;34(4):717-32. (PMID: 22098799) ; Cardiovasc Hematol Agents Med Chem. 2012 Jun;10(2):124-34. (PMID: 22471957) ; Nature. 2006 Dec 14;444(7121):860-7. (PMID: 17167474) ; Eur J Clin Invest. 2012 Dec;42(12):1287-94. (PMID: 23033884) ; Circ Res. 2005 May 13;96(9):939-49. (PMID: 15890981) ; Nutrients. 2021 Jan 23;13(2):. (PMID: 33498671) ; Cytokine. 2013 Feb;61(2):682-7. (PMID: 23306429) ; Ann Intern Med. 2016 Jun 7;164(11):740-51. (PMID: 27088241) ; J Hypertens. 2013 Sep;31(9):1819-27. (PMID: 23743811) ; Exp Ther Med. 2014 Jul;8(1):181-186. (PMID: 24944619) ; Nutrients. 2020 Feb 27;12(3):. (PMID: 32120798) ; Diabetes. 2008 Jun;57(6):1470-81. (PMID: 18305141) ; Clin Pharmacol Ther. 2010 Apr;87(4):407-16. (PMID: 20200516) ; Pediatr Gastroenterol Hepatol Nutr. 2013 Sep;16(3):143-52. (PMID: 24224147) ; Prostaglandins Leukot Essent Fatty Acids. 2009 Feb-Mar;80(2-3):85-91. (PMID: 19269799) ; Metabolism. 2018 Aug;85:32-37. (PMID: 29452178) ; J Nutr Biochem. 2018 Jun;56:1-15. (PMID: 29427903) ; JACC Heart Fail. 2013 Feb;1(1):1-20. (PMID: 24621794) ; Int Neurourol J. 2019 Nov;23(Suppl 2):S82-92. (PMID: 31795607) ; J Med Food. 2017 Apr;20(4):323-334. (PMID: 28346848) ; Curr Atheroscler Rep. 2013 May;15(5):324. (PMID: 23512608) ; J Zhejiang Univ Sci B. 2015 May;16(5):404-11. (PMID: 25990058) ; Diabetes Metab. 2014 Feb;40(1):76-81. (PMID: 24290615) ; J Clin Invest. 2007 Jan;117(1):175-84. (PMID: 17200717) ; Crit Rev Food Sci Nutr. 2017 Nov 2;57(16):3421-3429. (PMID: 26745681) ; Endocrinology. 2008 Nov;149(11):5679-87. (PMID: 18669592) ; BMJ. 2015 Jan 02;350:g7647. (PMID: 25555855) ; Neurochem Res. 2019 May;44(5):1065-1078. (PMID: 30820818) ; J Clin Invest. 2012 Jan;122(1):153-62. (PMID: 22201683) ; Eur J Nutr. 2021 Jan 2;:. (PMID: 33386893) ; BMC Med Res Methodol. 2014 Apr 01;14:45. (PMID: 24690082) ; Antioxidants (Basel). 2016 Sep 30;5(4):. (PMID: 27706020) ; Sci Rep. 2017 Jun 14;7(1):3451. (PMID: 28615667) ; Cent Eur J Public Health. 2021 Mar;29(1):38-44. (PMID: 33831285) ; Inflammopharmacology. 2017 Jun;25(3):313-328. (PMID: 28168552) ; Nutr Res. 2019 Jan;61:1-12. (PMID: 30683434) ; Arterioscler Thromb Vasc Biol. 2001 Jun;21(6):968-70. (PMID: 11397705) ; Biomed Pharmacother. 2002 Oct;56(8):365-79. (PMID: 12442909) ; Atherosclerosis. 2015 Jul;241(1):27-35. (PMID: 25957567) ; Acta Biochim Pol. 2018;65(3):465-470. (PMID: 30188965) ; Int J Mol Sci. 2020 Nov 27;21(23):. (PMID: 33261185) ; Mol Reprod Dev. 2015 Apr;82(4):321-8. (PMID: 25820748) ; Med Res Rev. 2019 Sep;39(5):1851-1891. (PMID: 30741437) ; Nutrients. 2020 Dec 27;13(1):. (PMID: 33375422) ; Arch Physiol Biochem. 2020 Jun 13;:1-6. (PMID: 32536220) ; Obes Rev. 2016 Mar;17(3):211-24. (PMID: 26783119) ; PLoS One. 2016 Apr 21;11(4):e0154003. (PMID: 27101398) ; Endocr Rev. 2008 Jun;29(4):494-511. (PMID: 18436709) ; Am J Cardiol. 1997 Sep 15;80(6):736-40. (PMID: 9315579) ; Nutrients. 2018 Mar 17;10(3):. (PMID: 29562604) ; Prog Cardiovasc Dis. 2014 Jan-Feb;56(4):369-81. (PMID: 24438728) ; Circulation. 2015 Jan 27;131(4):e29-322. (PMID: 25520374) ; Molecules. 2021 Feb 22;26(4):. (PMID: 33671813) ; J Cell Mol Med. 2010 Sep;14(9):2223-34. (PMID: 20716126) ; Nutrients. 2020 May 04;12(5):. (PMID: 32375317) ; Cytokine. 2015 Dec;76(2):514-518. (PMID: 26188367) ; J Cell Mol Med. 2011 Nov;15(11):2399-410. (PMID: 21143387) ; Adv Nutr. 2020 Mar 1;11(2):224-236. (PMID: 31329250) ; J Neurochem. 2018 Mar;144(5):527-548. (PMID: 28991365) ; Ther Adv Cardiovasc Dis. 2017 Aug;11(8):215-225. (PMID: 28639538) ; Res Dev Disabil. 2016 Oct;57:181-92. (PMID: 27448331) ; Curr Diabetes Rev. 2017;13(3):330-335. (PMID: 27296168) ; Nat Rev Cardiol. 2018 Dec;15(12):731-743. (PMID: 30115967) ; CMAJ. 2008 Jan 15;178(2):150. (PMID: 18195286) ; Circ Res. 2017 Jan 6;120(1):229-243. (PMID: 28057795) ; Asian Pac J Cancer Prev. 2015;16(10):4161-8. (PMID: 26028066) ; Cell Metab. 2011 Nov 2;14(5):612-22. (PMID: 22055504) ; Cardiorenal Med. 2013 Dec;3(4):265-82. (PMID: 24474955) ; JAMA. 2003 Apr 9;289(14):1799-804. (PMID: 12684358) ; Food Funct. 2018 Oct 17;9(10):5290-5300. (PMID: 30255184) ; Br J Nutr. 2012 Dec 28;108(12):2166-75. (PMID: 22414733) ; Food Funct. 2016 Feb;7(2):632-42. (PMID: 26786971) ; Inflammopharmacology. 2015 Jun;23(2-3):79-89. (PMID: 25676565) ; J Alzheimers Dis. 2009;16(4):693-704. (PMID: 19387106) ; Transl Stroke Res. 2019 Dec;10(6):639-649. (PMID: 30980283) ; Appl Physiol Nutr Metab. 2020 Oct;45(10):1055-1065. (PMID: 32717151) ; Circ Res. 2012 Mar 2;110(5):764-76. (PMID: 22383711) ; Obesity (Silver Spring). 2014 Feb;22(2):349-55. (PMID: 23640904) ; Diabetes. 2003 Apr;52(4):942-7. (PMID: 12663465) ; Eur J Nutr. 2021 Feb;60(1):29-44. (PMID: 32372266) ; J Diabetes Res. 2018 Nov 4;2018:3407306. (PMID: 30525052) ; Curr Hypertens Rep. 2020 Aug 29;22(9):74. (PMID: 32860083) ; Nutr Metab Cardiovasc Dis. 2011 Nov;21(11):851-6. (PMID: 20674311) ; Ann N Y Acad Sci. 2012 Aug;1264:13-9. (PMID: 22612379) ; Obes Rev. 2007 Jan;8(1):21-34. (PMID: 17212793) ; J Menopausal Med. 2014 Dec;20(3):90-6. (PMID: 25580419) ; J Nutr Sci Vitaminol (Tokyo). 2014;60(6):367-79. (PMID: 25866299) ; J Mol Cell Cardiol. 2008 Aug;45(2):270-80. (PMID: 18597775) ; Alzheimers Dement. 2019 Dec;15(12):1603-1611. (PMID: 31587996) ; Free Radic Res. 2019;53(sup1):1101-1112. (PMID: 31039629) ; Mediators Inflamm. 2010;2010:. (PMID: 20706689) ; Acta Endocrinol (Buchar). 2018 Jul-Sep;14(3):330-337. (PMID: 31149280) ; Am J Public Health. 2016 Sep;106(9):1656-62. (PMID: 27459460) ; Molecules. 2010 Oct 12;15(10):6993-7005. (PMID: 20944519) ; Endocrinology. 2004 May;145(5):2273-82. (PMID: 14726444) ; BMJ. 2016 Jan 28;352:i17. (PMID: 26823518) ; Endocr Metab Immune Disord Drug Targets. 2018;18(3):260-267. (PMID: 29384066) ; Respir Physiol Neurobiol. 2018 Jan;247:74-79. (PMID: 28963085) ; Eur Heart J. 2009 Apr;30(7):850-6. (PMID: 19136488) ; BMJ Open Sport Exerc Med. 2017 Mar 1;2(1):e000143. (PMID: 28879026) ; Molecules. 2021 Mar 05;26(5):. (PMID: 33807712) ; Exerc Sport Sci Rev. 2018 Jan;46(1):5-17. (PMID: 28885265) Contributed Indexing: Keywords: cardiovascular diseases; inflammation; inflammatory cytokines; metabolic syndrome; obesity Substance Nomenclature: 0 (Cytokines) Entry Date(s): Date Created: 20210505 Date Completed: 20210527 Latest Revision: 20210527 Update Code: 20231215 PubMed Central ID: PMC8125716

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Impact of Obesity-Induced Inflammation on Cardiovascular Diseases (CVD).