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Bortezomib-based regimens improve the prognosis of newly diagnosed MM patients with chromosomal aberrations except for del(17q13): A retrospective study from a single center.

Liu, Z ; Zeng, Q ; et al.
In: Medicine, Jg. 100 (2021-05-07), Heft 18, S. e25834
Online academicJournal

Titel:
Bortezomib-based regimens improve the prognosis of newly diagnosed MM patients with chromosomal aberrations except for del(17q13): A retrospective study from a single center.
Autor/in / Beteiligte Person: Liu, Z ; Zeng, Q ; Xiang, B
Link:
Zeitschrift: Medicine, Jg. 100 (2021-05-07), Heft 18, S. e25834
Veröffentlichung: Hagerstown, Md : Lippincott Williams & Wilkins, 2021
Medientyp: academicJournal
ISSN: 1536-5964 (electronic)
DOI: 10.1097/MD.0000000000025834
Schlagwort:
  • Adult
  • Aged
  • Aged, 80 and over
  • China epidemiology
  • Female
  • Humans
  • Kaplan-Meier Estimate
  • Male
  • Middle Aged
  • Multiple Myeloma genetics
  • Multiple Myeloma mortality
  • Prognosis
  • Progression-Free Survival
  • Retrospective Studies
  • Time Factors
  • Antineoplastic Combined Chemotherapy Protocols therapeutic use
  • Bortezomib therapeutic use
  • Chromosome Aberrations
  • Multiple Myeloma drug therapy
Sonstiges:
  • Nachgewiesen in: MEDLINE
  • Sprachen: English
  • Publication Type: Journal Article
  • Language: English
  • [Medicine (Baltimore)] 2021 May 07; Vol. 100 (18), pp. e25834.
  • MeSH Terms: Chromosome Aberrations* ; Antineoplastic Combined Chemotherapy Protocols / *therapeutic use ; Bortezomib / *therapeutic use ; Multiple Myeloma / *drug therapy ; Adult ; Aged ; Aged, 80 and over ; China / epidemiology ; Female ; Humans ; Kaplan-Meier Estimate ; Male ; Middle Aged ; Multiple Myeloma / genetics ; Multiple Myeloma / mortality ; Prognosis ; Progression-Free Survival ; Retrospective Studies ; Time Factors
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Bortezomib plus melphalan and prednisone for initial treatment of multiple myeloma. N Engl J Med 2008;359:906–17. ; Naymagon L, Abdul-Hay M. Novel agents in the treatment of multiple myeloma: a review about the future. J Hematol Oncol 2016;9:52. ; Gandolfi S, Paba Prada C, Richardson P. How I treat the young patient with multiple myeloma. Blood 2018;132:1114–24. ; Merz M, Jauch A, Hielscher T, et al. Longitudinal fluorescence in situ hybridization reveals cytogenetic evolution in myeloma relapsing after autologous transplantation. Haematologica 2017;102:1432–8. ; Merz M, Jauch A, Hielscher T, et al. Prognostic significance of cytogenetic heterogeneity in patients with newly diagnosed multiple myeloma. Blood Adv 2018;2:01–9. ; Zavrski I, Naujokat C, Niemoller K, et al. Proteasome inhibitors induce growth inhibition and apoptosis in myeloma cell lines and in human bone marrow myeloma cells irrespective of chromosome 13 deletion. 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  • Grant Information: 2019YFS0104 Department of Science and Technology of Sichuan Province
  • Substance Nomenclature: 69G8BD63PP (Bortezomib)
  • Entry Date(s): Date Created: 20210505 Date Completed: 20210520 Latest Revision: 20230103
  • Update Code: 20231215
  • PubMed Central ID: PMC8104214

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