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Since the discovery of horseradish peroxidase-like activity of magnetite nanoparticles in 2007, many researchers have investigated different types of nanoparticles that show enzyme-like activities, namely, nanozymes. Nanozymes possess high efficiency, stability, and low production costs compared to natural enzymes. Thus, nanozymes have already been widely studied in various domains including medical science, food industry, chemical engineering, and agriculture. This review presents the utilization of nanozymes in medicine and focuses particularly on their therapeutic applications in chronic inflammatory diseases because of their antioxidant-like activity. Furthermore, the treatment of chronic inflammatory diseases with nanozymes of different materials was introduced emphatically.

Competing Interests: All authors declare there is no conflict of interest.

Titel:	Therapeutic Applications of Nanozymes in Chronic Inflammatory Diseases.
Autor/in / Beteiligte Person:	Wang, H ; Cui, Z ; Wang, X ; Sun, S ; Zhang, D ; Fu, C
Link:	Full Text Finder (Volltext)
Zeitschrift:	BioMed research international, Jg. 2021 (2021-08-11), S. 9980127
Veröffentlichung:	New York, NY : Hindawi Pub. Co., 2021
Medientyp:	academicJournal
ISSN:	2314-6141 (electronic)
DOI:	10.1155/2021/9980127
Schlagwort:	Anti-Inflammatory Agents pharmacology Anti-Inflammatory Agents therapeutic use Biosensing Techniques Catalysis Drug Design Humans Magnetite Nanoparticles chemistry Anti-Inflammatory Agents chemical synthesis Inflammation drug therapy
Sonstiges:	Nachgewiesen in: MEDLINE Sprachen: English Publication Type: Journal Article; Review Language: English [Biomed Res Int] 2021 Aug 11; Vol. 2021, pp. 9980127. <i>Date of Electronic Publication: </i>2021 Aug 11 (<i>Print Publication: </i>2021). MeSH Terms: Anti-Inflammatory Agents / chemical synthesis ; Inflammation / drug therapy ; Anti-Inflammatory Agents / pharmacology ; Anti-Inflammatory Agents / therapeutic use ; Biosensing Techniques ; Catalysis ; Drug Design ; Humans ; Magnetite Nanoparticles / chemistry References: Adv Healthc Mater. 2013 Dec;2(12):1591-9. (PMID: 23630084) ; J Dairy Sci. 2018 Jul;101(7):5770-5779. (PMID: 29729911) ; Spectrochim Acta A Mol Biomol Spectrosc. 2019 Jan 15;207:236-241. (PMID: 30245138) ; Expert Opin Drug Saf. 2016;15(4):457-65. (PMID: 26789102) ; Anal Bioanal Chem. 2017 Jul;409(17):4225-4232. (PMID: 28493021) ; Biomaterials. 2016 Aug;98:92-102. (PMID: 27179436) ; Trends Pharmacol Sci. 2017 Aug;38(8):733-748. 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Therapeutic Applications of Nanozymes in Chronic Inflammatory Diseases.