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Objective: To assess the incidence of orthopaedic surgery (OS) (including total hip arthroplasty (THA), total knee arthroplasty, upper limb arthroplasty, arthrodesis and spinal surgery) and associated trends in patients with spondyloarthritis (SpA) over a long period (17 years).

Methods: An observational, retrospective, population-based, serial cross-sectional study was conducted. All hospital admissions of patients with SpA reported between 1999 and 2015 were analysed, and a control group was selected and matched by age, sex and year of admission. Incidence rates for OS (and subtypes) were calculated. Generalised linear models were used to analyse trends; unconditional logistic regression models were used to calculate crude and adjusted ORs (aORs) with the aim of evaluating the association between OS and SpA.

Results: The study database contained data on 214 280 hospital admissions (SpA/non-SpA 1:1 ratio). In the SpA cohort, 5 382 admissions (5.02%) had undergone OS compared with 3 533 in the non-SpA cohort (3.29%) (AOR 1.64; 95% CI 1.57 to 1.72). OS rates increased for both cohorts (+4.92% per year vs +8.41%). The trend in OS, THA, arthrodesis and spinal surgery decreased or stabilised in patients under age 60 in the SpA cohort, while the non-SpA cohort remained stable. In the SpA cohort, the mean age was 53.68 years (SD 13.65) in 1999, increasing to 62.76 years (SD 12.74) in 2015. In the non-SpA cohort, the mean age remained stable at around 63 years.

Conclusions: A 9-year difference in the age of patients undergoing OS was observed in patients with SpA. The incidence of OS, THA and arthrodesis decreased in patients under age 60, and the incidence of spinal surgery decreased in patients under age 40. Our findings suggest that these patients are increasingly able to defer surgical interventions.

Competing Interests: Competing interests: RM has received research funding from Pfizer, Roche, and Amgen for this and other projects.

Titel:	Trends in orthopaedic surgery for spondyloarthritis: outcomes from a National Hospitalised Patient Registry (MBDS) over a 17-year period (1999-2015).TREND-EspA study.
Autor/in / Beteiligte Person:	Mazzucchelli, R ; Almodóvar, R ; Turrado-Crespí, P ; Crespí-Villarías, N ; Pérez-Fernández, E ; García-Zamora, E ; García-Vadillo, A
Link:	Full Text Finder (Volltext)
Zeitschrift:	RMD open, Jg. 8 (2022-03-01), Heft 1
Veröffentlichung:	London : BMJ Publishing Group, [2015]-, 2022
Medientyp:	academicJournal
ISSN:	2056-5933 (electronic)
DOI:	10.1136/rmdopen-2021-002107
Schlagwort:	Adult Cross-Sectional Studies Humans Middle Aged Registries Retrospective Studies Arthroplasty, Replacement, Hip adverse effects Orthopedic Procedures Spondylarthritis epidemiology Spondylarthritis surgery
Sonstiges:	Nachgewiesen in: MEDLINE Sprachen: English Publication Type: Journal Article; Observational Study; Research Support, Non-U.S. Gov't Language: English [RMD Open] 2022 Mar; Vol. 8 (1). MeSH Terms: Arthroplasty, Replacement, Hip* / adverse effects ; Orthopedic Procedures* ; Spondylarthritis* / epidemiology ; Spondylarthritis* / surgery ; Adult ; Cross-Sectional Studies ; Humans ; Middle Aged ; Registries ; Retrospective Studies References: Arthritis Rheum. 2007 Apr 15;57(3):529-32. (PMID: 17394183) ; J Am Acad Orthop Surg. 2013 Jun;21(6):355-63. (PMID: 23728960) ; Reumatol Clin (Engl Ed). 2019 Mar - Apr;15(2):90-96. (PMID: 28774657) ; RMD Open. 2021 Sep;7(3):. (PMID: 34593628) ; Ann Rheum Dis. 2019 Nov;78(11):1517-1523. (PMID: 31300461) ; J Rheumatol. 2018 Aug;45(9):1334-1336. (PMID: 30173183) ; Health Policy. 2014 Jan;114(1):15-30. (PMID: 24035101) ; RMD Open. 2016 Aug 17;2(2):e000293. (PMID: 27651927) ; Arthritis Rheum. 1998 Jun;41(6):1072-82. (PMID: 9627017) ; J Rheumatol. 2018 Nov;45(11):1532-1540. (PMID: 30173150) ; Arthritis Rheum. 2004 Apr;50(4):1122-31. (PMID: 15077294) ; J Clin Epidemiol. 1992 Jun;45(6):613-9. (PMID: 1607900) ; Ann Rheum Dis. 2004 Jan;63(1):4-10. (PMID: 14672883) ; J Rheumatol. 2019 Jan;46(1):31-37. (PMID: 29961693) ; Ann Rheum Dis. 2008 Oct;67(10):1412-6. (PMID: 18178691) ; Lancet. 2011 Jun 18;377(9783):2127-37. (PMID: 21684383) ; Arthritis Care Res (Hoboken). 2019 Nov;71(11):1525-1529. (PMID: 30354036) ; Int Orthop. 2011 Dec;35(12):1783-9. (PMID: 21404023) ; Ann Transl Med. 2017 Dec;5(Suppl 3):S29. (PMID: 29299476) ; Arthritis Rheumatol. 2014 Jun;66(6):1432-9. (PMID: 24591462) ; Ann Rheum Dis. 2004 Jul;63(7):825-30. (PMID: 15194578) ; J Rheumatol. 2020 Mar;47(3):341-348. (PMID: 31203231) ; Nat Rev Dis Primers. 2015 Jul 09;1:15013. (PMID: 27188328) ; Med Care. 2018 Sep;56(9):812-813. (PMID: 30059362) ; J Arthroplasty. 2012 Jun;27(6):881-8. (PMID: 22333866) ; J Rheumatol. 2002 Jan;29(1):52-6. (PMID: 11824971) ; Ann Rheum Dis. 2014 Jun;73(6):1194-7. (PMID: 24285490) Contributed Indexing: Keywords: epidemiology; orthopedic surgery; spondyloarthritis Entry Date(s): Date Created: 20220317 Date Completed: 20220405 Latest Revision: 20220526 Update Code: 20231215 PubMed Central ID: PMC8928380

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Trends in orthopaedic surgery for spondyloarthritis: outcomes from a National Hospitalised Patient Registry (MBDS) over a 17-year period (1999-2015).TREND-EspA study.