COVID-19 related peripheral arterial thrombotic events in intensive care unit and non-intensive care unit patients: A retrospective case series.
In: Vascular, Jg. 32 (2024-04-01), Heft 2, S. 366-373
Online
academicJournal
Zugriff:
Objectives: COVID-19 associated arterial thrombosis has been attributed to multiple inflammation and coagulation mechanisms. The aim of this study was to report the experience of a tertiary center on COVID-19 patients managed for acute peripheral arterial thrombosis.
Methods: A single-center case series was conducted, including retrospectively collected data from all COVID-19 patients presenting arterial thrombosis, from March 2020 to February 2022. Intensive care unit (ICU) and non-ICU cases were included. The primary outcomes were mortality, successful revascularization, and amputation at 30 days.
Results: Twenty patients presented peripheral arterial thrombosis (90% males, mean age 65 years (16-82 years)). Eighteen were diagnosed with the Delta variant and none was previously vaccinated. All cases presented acute lower limb ischemia; in 20% with bilateral involvement. Nine patients were hospitalized in the ward while 11 in the ICU. From the non-ICU cases, five presented Rutherford IIb and four cases, Rutherford's IIa ischemia. Six cases underwent revascularization (67%). Two of them were finally amputated (33%) and two died during hospitalization (33%). Two revascularizations were considered successful (33%). The ICU group presented mainly with Rutherford's III ischemia (54.5%). The mortality in the ICU cohort was 72.7%. Only one patient underwent successful revascularization and two were amputated in this subgroup. Early mortality was 50% for the total cohort while the type of management was not related to mortality.
Conclusions: Covid-19 related arterial thrombosis in non-vaccinated population is associated with 50% early mortality; increased up to 72% in the ICU patients. The amputation rate was 20% while only 40% of the revascularizations were considered successful.
Competing Interests: Declaration of conflicting interestsThe author(s) declared no potential conflicts of interest with respect to the research, authorship, and/or publication of this article.
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COVID-19 related peripheral arterial thrombotic events in intensive care unit and non-intensive care unit patients: A retrospective case series.
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Autor/in / Beteiligte Person: | Nana, P ; Dakis, K ; Spanos, K ; Tsolaki, V ; Karavidas, N ; Zakynthinos, G ; Kouvelos, G ; Giannoukas, A ; Matsagkas, M |
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Zeitschrift: | Vascular, Jg. 32 (2024-04-01), Heft 2, S. 366-373 |
Veröffentlichung: | Dec. 2012- : London : Sage ; <i>Original Publication</i>: Hamilton, Ont., Canada : BC Decker, [2004]-, 2024 |
Medientyp: | academicJournal |
ISSN: | 1708-539X (electronic) |
DOI: | 10.1177/17085381221140159 |
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