Disrupting Maternal Transmission of Depression: Using Integrative Data Analysis (IDA) to Examine Indirect Effects of the Family Check-Up (FCU) Across Three Randomized Trials.

Seidman, S ; Connell, A ; et al.

In: Prevention science : the official journal of the Society for Prevention Research, Jg. 24 (2023-11-01), Heft 8, S. 1523-1534

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Maternal depression is a well-established risk factor for the development of depression in offspring. As such, reducing maternal depression may be key to effective prevention efforts to reduce offspring's depression. Based on the broad risk represented by maternal depression, examining cross-over effects of parent-focused interventions on maternal depression is important. The present study examined improvements in maternal depression as a mediator of the long-term effects of the Family Check-Up (FCU) prevention program on youth depression across three randomized controlled trials. The FCU is a family-focused intervention originally designed to reduce youth problem behaviors, particularly conduct problems and substance use, but has also been found to have cross-over effects on other youth problem behaviors, including internalizing symptoms. We utilized integrative data analysis that allows for powerful tests of prevention effects across trials, specifically moderated nonlinear factor analysis, to integrate data across three trials: one trial initiated in early childhood and two in early adolescence. Using a latent growth modeling approach, we first examined direct effects of the FCU on changes in maternal depression. Then we examined the mediating effect of maternal depression on changes in both parent and youth reports of youth depression. A significant intervention effect on maternal depression was observed across the three trials, with the FCU predicting improvements in maternal depression. In turn, such improvements predicted a reduction in the growth in both parent and youth reports of youth depressive symptoms across 10 years post baseline. These results demonstrate the utility in addressing cross-over effects of family-focused interventions in reducing the long-term development of depression in youth through mediating pathways.

Titel:	Disrupting Maternal Transmission of Depression: Using Integrative Data Analysis (IDA) to Examine Indirect Effects of the Family Check-Up (FCU) Across Three Randomized Trials.
Autor/in / Beteiligte Person:	Seidman, S ; Connell, A ; Stormshak, E ; Westling, E ; Ha, T ; Shaw, D
Link:	Full Text Finder (Volltext)
Zeitschrift:	Prevention science : the official journal of the Society for Prevention Research, Jg. 24 (2023-11-01), Heft 8, S. 1523-1534
Veröffentlichung:	New York, NY : Kluwer Academic/Plenum Publishers, c2000-, 2023
Medientyp:	academicJournal
ISSN:	1573-6695 (electronic)
DOI:	10.1007/s11121-022-01471-4
Schlagwort:	Adolescent Humans Child, Preschool Randomized Controlled Trials as Topic Family Data Analysis Depression prevention & control Parents
Sonstiges:	Nachgewiesen in: MEDLINE Sprachen: English Publication Type: Journal Article Language: English [Prev Sci] 2023 Nov; Vol. 24 (8), pp. 1523-1534. <i>Date of Electronic Publication: </i>2022 Dec 31. MeSH Terms: Depression* / prevention & control ; Parents* ; Adolescent ; Humans ; Child, Preschool ; Randomized Controlled Trials as Topic ; Family ; Data Analysis References: J Res Adolesc. 2016 Mar;26(1):76-89. (PMID: 27034608) ; Psychol Methods. 2010 Dec;15(4):309-34. (PMID: 20954780) ; J Fam Psychol. 2007 Sep;21(3):398-406. (PMID: 17874925) ; Prev Sci. 2016 Apr;17(3):377-85. (PMID: 26687204) ; Gen Hosp Psychiatry. 2016 Mar-Apr;39:39-45. (PMID: 26791259) ; Psychiatr Clin North Am. 2012 Mar;35(1):1-14. (PMID: 22370487) ; Psychol Aging. 2009 Mar;24(1):184-9. (PMID: 19290750) ; J Educ Psychol. 2013 Aug 1;105(3):. (PMID: 24319295) ; J Consult Clin Psychol. 2019 Nov;87(11):1056-1067. (PMID: 31556651) ; Can J Psychiatry. 2020 Jun;65(6):392-400. (PMID: 31830819) ; Psychol Methods. 2002 Mar;7(1):83-104. (PMID: 11928892) ; Clin Psychol Rev. 2011 Nov;31(7):1117-25. (PMID: 21820991) ; Psychol Rev. 1999 Jul;106(3):458-90. (PMID: 10467895) ; J Fam Psychol. 2008 Aug;22(4):574-85. (PMID: 18729671) ; Child Dev. 2008 Sep-Oct;79(5):1395-414. (PMID: 18826532) ; J Child Fam Stud. 2016;25(11):3173-3191. (PMID: 27795657) ; J Clin Child Adolesc Psychol. 2006 Dec;35(4):490-503. (PMID: 17007595) ; J Am Acad Child Adolesc Psychiatry. 2000 Jan;39(1):28-38. (PMID: 10638065) ; J Consult Clin Psychol. 2015 Dec;83(6):1142-8. (PMID: 26302250) ; Annu Rev Clin Psychol. 2013;9:61-89. (PMID: 23394226) ; Dev Psychopathol. 2009 Spring;21(2):417-39. (PMID: 19338691) ; J Fam Psychol. 2016 Feb;30(1):82-92. (PMID: 26414418) ; J Abnorm Child Psychol. 2014;42(3):343-54. (PMID: 24022677) ; Psychol Methods. 2009 Jun;14(2):101-25. (PMID: 19485624) ; J Abnorm Child Psychol. 2019 Mar;47(3):459-474. (PMID: 29808395) ; Prev Sci. 2018 Feb;19(Suppl 1):16-26. (PMID: 26267390) ; J Abnorm Child Psychol. 2018 May;46(4):825-837. (PMID: 28643207) ; Addict Behav. 2012 Dec;37(12):1314-24. (PMID: 22958864) ; J Consult Clin Psychol. 2021 Sep;89(9):773-782. (PMID: 34591550) ; Suicide Life Threat Behav. 2016 Apr;46 Suppl 1:S15-22. (PMID: 27094106) ; Stress Health. 2020 Apr;36(2):107-118. (PMID: 31612594) ; Clin Child Fam Psychol Rev. 2011 Mar;14(1):1-27. (PMID: 21052833) ; Addict Behav. 2019 Jul;94:65-73. (PMID: 30385076) ; Dev Psychopathol. 2019 Dec;31(5):1901-1910. (PMID: 31370914) ; J Clin Child Adolesc Psychol. 2014;43(3):400-14. (PMID: 24731120) ; J Am Acad Child Adolesc Psychiatry. 1998 Sep;37(9):906-14. (PMID: 9735610) ; Am J Orthopsychiatry. 2016 Jan;86(1):61-8. (PMID: 26460697) Grant Information: R01 DA018374 United States DA NIDA NIH HHS; R01 AA022071 United States AA NIAAA NIH HHS; MH122213 United States MH NIMH NIH HHS; R01 HD075150 United States HD NICHD NIH HHS; AA022071 United States AA NIAAA NIH HHS; DA25630 United States DA NIDA NIH HHS; DA018374 United States DA NIDA NIH HHS; R01 MH122213 United States MH NIMH NIH HHS; R01 DA026222 United States DA NIDA NIH HHS; R01 DA007031 United States DA NIDA NIH HHS; R37 DA007031 United States DA NIDA NIH HHS; DA07031 United States DA NIDA NIH HHS; DA26222 United States DA NIDA NIH HHS; K05 DA025630 United States DA NIDA NIH HHS Contributed Indexing: Keywords: Adolescence; Childhood; Depression; Family Check-up; Parenting; Prevention Entry Date(s): Date Created: 20221231 Date Completed: 20231128 Latest Revision: 20240218 Update Code: 20240218 PubMed Central ID: PMC10789115

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