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Immunoregulatory role of hesperidin against ovalbumin (OVA)-induced bronchial asthma and depression in rats.

Salama, A ; Gouida, MSO ; et al.
In: Naunyn-Schmiedeberg's archives of pharmacology, Jg. 397 (2024-05-01), Heft 5, S. 3363-3378
Online academicJournal

Titel:
Immunoregulatory role of hesperidin against ovalbumin (OVA)-induced bronchial asthma and depression in rats.
Autor/in / Beteiligte Person: Salama, A ; Gouida, MSO ; Yassen, NN ; Sedik, AA
Link:
Zeitschrift: Naunyn-Schmiedeberg's archives of pharmacology, Jg. 397 (2024-05-01), Heft 5, S. 3363-3378
Veröffentlichung: Berlin, New York, Springer Verlag., 2024
Medientyp: academicJournal
ISSN: 1432-1912 (electronic)
DOI: 10.1007/s00210-023-02833-7
Schlagwort:
  • Animals
  • Male
  • Rats
  • Immunoglobulin E blood
  • Brain drug effects
  • Brain metabolism
  • Brain pathology
  • Brain immunology
  • Motor Activity drug effects
  • Cytokines metabolism
  • Behavior, Animal drug effects
  • Serotonin metabolism
  • Disease Models, Animal
  • Hesperidin pharmacology
  • Hesperidin therapeutic use
  • Asthma drug therapy
  • Asthma immunology
  • Asthma chemically induced
  • Ovalbumin immunology
  • Depression drug therapy
  • Rats, Wistar
  • Lung drug effects
  • Lung pathology
  • Lung immunology
  • Lung metabolism
Sonstiges:
  • Nachgewiesen in: MEDLINE
  • Sprachen: English
  • Publication Type: Journal Article; Research Support, Non-U.S. Gov't
  • Language: English
  • [Naunyn Schmiedebergs Arch Pharmacol] 2024 May; Vol. 397 (5), pp. 3363-3378. <i>Date of Electronic Publication: </i>2023 Nov 11.
  • MeSH Terms: Hesperidin* / pharmacology ; Hesperidin* / therapeutic use ; Asthma* / drug therapy ; Asthma* / immunology ; Asthma* / chemically induced ; Ovalbumin* / immunology ; Depression* / drug therapy ; Rats, Wistar* ; Lung* / drug effects ; Lung* / pathology ; Lung* / immunology ; Lung* / metabolism ; Animals ; Male ; Rats ; Immunoglobulin E / blood ; Brain / drug effects ; Brain / metabolism ; Brain / pathology ; Brain / immunology ; Motor Activity / drug effects ; Cytokines / metabolism ; Behavior, Animal / drug effects ; Serotonin / metabolism ; Disease Models, Animal
  • References: Abdel-Fattah MM, Salama AA, Shehata BA, Ismaiel IE (2015) The potential effect of the angiotensin II receptor blocker telmisartan in regulating OVA-induced airway remodeling in experimental rats. Pharmacol Rep 67:943–951. (PMID: 26398389) ; Afifi NA, Ramadan A, Erian EY, Sedik AA, Amin MM, Hassan A, Saleh DO (2021) Synergistic effect of aminoguanidine and l-carnosine against thioacetamide-induced hepatic encephalopathy in rats: behavioral, biochemical, and ultrastructural evidence. Can J Physiol Pharmacol 99:332–347. (PMID: 32721224) ; Andreone S (2023) Eosinophils acquire immune checkpoint molecules through trogocytosis: implications in cancer immunity. ; Asfour MH, Kassem AA, Salama A, Abd El-Alim SH (2020) Hydrophobic ion pair loaded self-emulsifying drug delivery system (SEDDS): a novel oral drug delivery approach of cromolyn sodium for management of bronchial asthma. Int J Pharm 585:119494. (PMID: 32505578) ; Bajgelman MC (2019) Principles and applications of flow cytometry. Data Processing Handbook for Complex Biological Data Sources. Elsevier, pp. 119-124. ; Barnes PJ (2001) Cytokine-directed therapies for asthma. J Allergy Clin Immunol 108:S72–S76. (PMID: 11498676) ; Cai L, Li R, Wu Q-Q, Wu T-N (2013) Effect of hesperidin on behavior and HPA axis of rat model of chronic stress-induced depression. Zhongguo Zhong yao za zhi= Zhongguo zhongyao zazhi=. China J Chinese Materia Med 38:229–233. ; Carleton HM, Drury RAB, Wallington EA (1980) Carleton’s histological technique. Oxford University Press, USA. ; Catal F, Mete E, Tayman C, Topal E, Albayrak A, Sert H (2015) A human monoclonal anti-TNF alpha antibody (adalimumab) reduces airway inflammation and ameliorates lung histology in a murine model of acute asthma. Allergol Immunopathol 43:14–18. ; Chen W, Sivaprasad U, Gibson AM, Ericksen MB, Cunningham CM, Bass SA, Kinker KG, Finkelman FD, Wills-Karp M, Hershey GKK (2013) IL-13 receptor α2 contributes to development of experimental allergic asthma. J Allergy Clin Immunol 132(951-958):e956. ; Cheng B-H, Hu T-Y, Mo L-H, Hu W-H, Li Y-S, Liu Z-Q, Qiu S-Q (2019) Yan-Hou-Qing formula attenuates allergic airway inflammation via up-regulation of Treg and suppressing Th2 responses in ovalbumin-induced asthmatic mice. J Ethnopharmacol 231:275–282. (PMID: 30496840) ; Choi S, Yu S, Lee J, Kim W (2021) Effects of neohesperidin dihydrochalcone (NHDC) on oxidative phosphorylation, cytokine production, and lipid deposition. Foods 10:1408. (PMID: 342070688233977) ; Conrad M, Yildirim A, Sonar S, Kılıç A, Sudowe S, Lunow M, Teich R, Renz H, Garn H (2009) Comparison of adjuvant and adjuvant-free murine experimental asthma models. Clin Exp Allergy 39:1246–1254. (PMID: 194385852728898) ; Cryan JF, Valentino RJ, Lucki I (2005) Assessing substrates underlying the behavioral effects of antidepressants using the modified rat forced swimming test. Neurosci Biobehav Rev 29:547–569. (PMID: 15893822) ; de Souza ABF, de Matos NA, de Freitas CT, de Paula CG, Oliveira LAM, Nogueira KOPC, Ribeiro IML, Talvani A, Cangussú SD, de Menezes RCA (2022) Effects in vitro and in vivo of hesperidin administration in an experimental model of acute lung inflammation. Free Radic Biol Med 180:253–262. (PMID: 35092853) ; Devi KP, Rajavel T, Nabavi SF, Setzer WN, Ahmadi A, Mansouri K, Nabavi SM (2015) Hesperidin: a promising anticancer agent from nature. Ind Crop Prod 76:582–589. ; Dong F, Wang C, Duan J, Zhang W, Xiang D (2014) Li M (2014) Puerarin attenuates ovalbumin-induced lung inflammation and hemostatic unbalance in rat asthma model. Evid Based Complement Alternat Med. ; Dowlati Y, Herrmann N, Swardfager W, Liu H, Sham L, Reim EK, Lanctôt KL (2010) A meta-analysis of cytokines in major depression. Biol Psychiatry 67:446–457. (PMID: 20015486) ; Enejoh OS, Ogunyemi IO, Bala MS, Oruene IS, Suleiman MM, Ambali SF (2015) Ethnomedical importance of Citrus aurantifolia (christm) swingle. Pharm Innov 4:1. ; Feng D-d, Tang T, Lin X-p, Yang Z-y, Yang S, Xia Z-a, Wang Y, Zheng P, Wang Y, Zhang C-h (2016) Nine traditional Chinese herbal formulas for the treatment of depression: an ethnopharmacology, phytochemistry, and pharmacology review. Neuropsychiatr Dis Treat:2387–2402. ; Forastiere F, Pistelli R, Sestini P, Fortes C, Renzoni E, Rusconi F, Dellr’Oco V, Ciccone G, Bisanti L, Group SC (2000) Consumption of fresh fruit rich in vitamin C and wheezing symptoms in children. Thorax 55:283–288. (PMID: 107227671745721) ; Fu H, Liu L, Tong Y, Li Y, Zhang X, Gao X, Yong J, Zhao J, Xiao D, Wen K (2019) The antidepressant effects of hesperidin on chronic unpredictable mild stress-induced mice. Eur J Pharmacol 853:236–246. (PMID: 30928632) ; Ganeshpurkar A, Saluja A (2019) In silico interaction of hesperidin with some immunomodulatory targets: a docking analysis. Indian J Biochem Biophy (IJBB) 56:28–33. ; Garg A, Garg S, Zaneveld L, Singla A (2001) Chemistry and pharmacology of the citrus bioflavonoid hesperidin. Phytother Res 15:655–669. (PMID: 11746857) ; Greenfeder S, Umland SP, Cuss FM, Chapman RW, Egan RW (2001) Th2 cytokines and asthma the role of interleukin-5 in allergic eosinophilic disease. Respir Res 2:1–9. ; Hajialyani M, Hosein Farzaei M, Echeverría J, Nabavi SM, Uriarte E, Sobarzo-Sánchez E (2019) Hesperidin as a neuroprotective agent: a review of animal and clinical evidence. Molecules 24:648. (PMID: 307598336384806) ; Hasanin AH, Matboli M, Seleem HS (2020) Hesperidin suppressed hepatic precancerous lesions via modulation of exophagy in rats. J Cell Biochem 121:1295–1306. (PMID: 31489981) ; Hedges D, Farrer TJ, Bigler ED, Hopkins RO, Hedges D, Farrer TJ, Bigler ED, Hopkins RO (2019) Cognitive function in pulmonary disease. The Brain at Risk, Associations between Disease and Cognition, pp 245–268. ; Holmes K, Lantz LM, Fowlkes B, Schmid I, Giorgi JV (2001) Preparation of cells and reagents for flow cytometry. Current Protocols in immunology 44: 5.3. 1-5.3. 24. ; Iglesias DJ, Cercós M, Colmenero-Flores JM, Naranjo MA, Ríos G, Carrera E, Ruiz-Rivero O, Lliso I, Morillon R, Tadeo FR (2007) Fisiologia da frutificação em citrus. Braz J Plant Physiol 19:333–362. ; Jang H-Y, Ahn K-S, Park M-J, Kwon O-K, Lee H-K, Oh S-R (2012) Skullcapflavone II inhibits ovalbumin-induced airway inflammation in a mouse model of asthma. Int Immunopharmacol 12:666–674. (PMID: 22314230) ; Jeffery P, Godfrey R, Ädelroth E, Nelson F, Rogers A, Johansson S-A (2012) Effects of treatment on airway inflammation and thickening of basement membrane reticular collagen in asthma: a quantitative light and electron microscopic study. Am Rev Respir Dis. ; Kelly EB (2022) What You Need to Know about Asthma. ABC-CLIO. ; Kim S-H, Kim B-K (2011) Lee Y-C (2011) Antiasthmatic effects of hesperidin, a potential Th2 cytokine antagonist, in a mouse model of allergic asthma. Mediat Inflamm. ; Ko JW, Kwon HJ, Seo CS, Choi SJ, Shin NR, Kim SH, Kim YH, Kim JC, Kim MS, Shin IS (2020) 4-Hydroxycinnamic acid suppresses airway inflammation and mucus hypersecretion in allergic asthma induced by ovalbumin challenge. Phytother Res 34:624–633. (PMID: 31724257) ; Kroll JL, Steele AM, Pinkham AE, Choi C, Khan DA, Patel SV, Chen JR, Aslan S, Brown ES, Ritz T (2018) Hippocampal metabolites in asthma and their implications for cognitive function. NeuroImage: Clin 19:213–221. (PMID: 30035015) ; Lee J, Yu H, Wang L, Yang Y, Lin Y, Chiang B (2007) The levels of CD4+ CD25+ regulatory T cells in paediatric patients with allergic rhinitis and bronchial asthma. Clin Exp Immunol 148:53–63. (PMID: 173490111868849) ; Li C, Zug C, Qu H, Schluesener H, Zhang Z (2015) Hesperidin ameliorates behavioral impairments and neuropathology of transgenic APP/PS1 mice. Behav Brain Res 281:32–42. (PMID: 25510196) ; Lloyd CM, Hawrylowicz CM (2009) Regulatory T cells in asthma. Immunity 31:438–449. (PMID: 197660863385348) ; Loerbroks A, Herr RM, Subramanian S, Bosch JA (2012) The association of asthma and wheezing with major depressive episodes: an analysis of 245 727 women and men from 57 countries. Int J Epidemiol 41:1436–1444. (PMID: 22879363) ; Lukacs NW (2001) Role of chemokines in the pathogenesis of asthma. Nat Rev Immunol 1:108–116. (PMID: 11905818) ; Lv X, Zhao S, Ning Z, Zeng H, Shu Y, Tao O, Xiao C, Lu C, Liu Y (2015) Citrus fruits as a treasure trove of active natural metabolites that potentially provide benefits for human health. Chem Central J 9:1–14. ; Ma C, Zou L, Xia Y, Tu Y, Xue D, Yang Y, Liu D, Liu Y, Wu H, Dan H (2019) Extracts of Coleus forskohlii relieves cough and asthma symptoms via modulating inflammation and the extracellular matrix. J Cell Biochem 120:9648–9655. (PMID: 30520122) ; Marazioti A, Kastellakis A, Antoniou K, Papasava D, Thermos K (2005) Somatostatin receptors in the ventral pallidum/substantia innominata modulate rat locomotor activity. Psychopharmacology 181:319–326. (PMID: 15778878) ; Maslan J, Mims JW (2014) What is asthma? Pathophysiology, demographics, and health care costs. Otolaryngol Clin N Am 47:13–22. ; Mauser PJ, Pitman A, Witt A, Fernandez X, Zurcher J, Kung T, Jones H, Watnick AS, Egan RW, Kreutner W (1993) Inhibitory effect of the TRFK-5 anti-IL-5 antibody in guinea pig model of asthma. Am Rev Respir Dis 148:1623–1623. (PMID: 7504892) ; Meneguzzo F, Ciriminna R, Zabini F, Pagliaro M (2020) Review of evidence available on hesperidin-rich products as potential tools against COVID-19 and hydrodynamic cavitation-based extraction as a method of increasing their production. Processes 8:549. ; Miller CN, Yang JY, Avra T, Ambati S, Della-Fera MA, Rayalam S, Baile CA (2015) A dietary phytochemical blend prevents liver damage associated with adipose tissue mobilization in ovariectomized rats. Obesity 23:112–119. (PMID: 25451038) ; Moldoveanu B, Otmishi P, Jani P, Walker J, Sarmiento X, Guardiola J, Saad M, Yu J (2008) Inflammatory mechanisms in the lung. J Inflamm Res:1–11. ; Nagashio Y, Matsuura Y, Miyamoto J, Kometani T, Suzuki T, Tanabe S (2013) Hesperidin inhibits development of atopic dermatitis-like skin lesions in NC/Nga mice by suppressing Th17 activity. J Funct Foods 5:1633–1641. ; Nakao A (2001) Is TGF-β1 the key to suppression of human asthma? Trends Immunol 22:115–118. (PMID: 11286715) ; Ogawa Y, Duru EA, Ameredes BT (2008) Role of IL-10 in the resolution of airway inflammation. Curr Mol Med 8:437–445. (PMID: 186910719159958) ; Opolski M, Wilson I (2005) Asthma and depression: a pragmatic review of the literature and recommendations for future research. Clin Pract Epidemiol Ment Health 1:1–7. ; Otsuki K, Uchida S, Watanuki T, Wakabayashi Y, Fujimoto M, Matsubara T, Funato H, Watanabe Y (2008) Altered expression of neurotrophic factors in patients with major depression. J Psychiatr Res 42:1145–1153. (PMID: 18313696) ; Périz M, Pérez-Cano FJ, Rodríguez-Lagunas MJ, Cambras T, Pastor-Soplin S, Best I, Castell M, Massot-Cladera M (2020) Development and characterization of an allergic asthma rat model for interventional studies. Int J Mol Sci 21:3841. (PMID: 324816757312681) ; Possa SS, Leick EA, Prado CM, Martins MA, Tibério IF (2013) Eosinophilic inflammation in allergic asthma. Front Pharmacol 4:46. (PMID: 236167683627984) ; Ray A, Khare A, Krishnamoorthy N, Qi Z, Ray P (2010) Regulatory T cells in many flavors control asthma. Mucosal Immunol 3:216–229. (PMID: 201648323039023) ; Renauld J-C (2001) New insights into the role of cytokines in asthma. J Clin Pathol 54:577–589. (PMID: 114771111731485) ; Renz H (2001) Neurotrophins in bronchial asthma. Respir Res 2:1–4. ; Saini RK, Ranjit A, Sharma K, Prasad P, Shang X, Gowda KGM, Keum Y-S (2022) Bioactive compounds of citrus fruits: a review of composition and health benefits of carotenoids, flavonoids, limonoids, and terpenes. Antioxidants 11:239. (PMID: 352041228868476) ; Salama A, Elgohary R (2021) L-carnitine and Co Q10 ameliorate potassium dichromate-induced acute brain injury in rats targeting AMPK/AKT/NF-κβ. Int Immunopharmacol 101:107867. (PMID: 34489184) ; Sandeep T, Roopakala MS, Silvia CRWD, Chandrashekara S, Rao M (2010) Evaluation of serum immunoglobulin E levels in bronchial asthma. Lung India: official Organ Indian Chest Soc 27:138. ; Sedik AA, Elgohary R (2023) Neuroprotective effect of tangeretin against chromium-induced acute brain injury in rats: targeting Nrf2 signaling pathway, inflammatory mediators, and apoptosis. Inflammopharmacology:1–16. ; Sedik AA, Hassan A, Saleh DO (2023) Neuromodulatory role of L-arginine: nitric oxide precursor against thioacetamide-induced-hepatic encephalopathy in rats via downregulation of NF-κB-mediated apoptosis. Environ Sci Pollut Res:1–14. ; Sherkawy MM, Abo-Youssef AM, Salama AA, Ismaiel IE (2018) Fluoxetine protects against OVA induced bronchial asthma and depression in rats. Eur J Pharmacol 837:25–32. (PMID: 30145150) ; Sheth A, Reddymasu S, Jackson R (2006) Worsening of asthma with systemic corticosteroids: a case report and review of literature. J Gen Intern Med 21:C11–C13. (PMID: 166063751484654) ; Smith A, Krishnan JA, Bilderback A, Riekert KA, Rand CS, Bartlett SJ (2006) Depressive symptoms and adherence to asthma therapy after hospital discharge. Chest 130:1034–1038. (PMID: 17035435) ; Tanaka T, Takahashi R (2013) Flavonoids and asthma. Nutrients 5:2128–2143. (PMID: 237524943725497) ; Tejada S, Pinya S, Martorell M, Capó X, Tur JA, Pons A, Sureda A (2018) Potential anti-inflammatory effects of hesperidin from the genus citrus. Curr Med Chem 25:4929–4945. (PMID: 28721824) ; Van Lieshout RJ, Bienenstock J, MacQueen GM (2009) A review of candidate pathways underlying the association between asthma and major depressive disorder. Psychosom Med 71:187–195. (PMID: 19073754) ; Wang J, Fu Y, Wei Z, He X, Shi M, Kou J, Zhou E, Liu W, Yang Z, Guo C (2017) Anti-asthmatic activity of osthole in an ovalbumin-induced asthma murine model. Respir Physiol Neurobiol 239:64–69. (PMID: 28143779) ; Zelová H, Hošek J (2013) TNF-α signalling and inflammation: interactions between old acquaintances. Inflamm Res 62:641–651. (PMID: 23685857) ; Zielinski TA, Brown ES, Nejtek VA, Khan DA, Moore JJ, Rush AJ (2000) Depression in asthma: prevalence and clinical implications. Primary Care Comp J Clin Psych 2:153.
  • Contributed Indexing: Keywords: Bronchial asthma; Depression; Hesperidin; Ovalbumin
  • Substance Nomenclature: E750O06Y6O (Hesperidin) ; 9006-59-1 (Ovalbumin) ; 37341-29-0 (Immunoglobulin E) ; 0 (Cytokines) ; 333DO1RDJY (Serotonin)
  • Entry Date(s): Date Created: 20231111 Date Completed: 20240506 Latest Revision: 20240620
  • Update Code: 20240620
  • PubMed Central ID: PMC11074047

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