Einzeltreffer — DigiBib

Background: We test a novel 'weight scarring' hypothesis which suggests that past obesity is associated with impairments in current psychological well-being and this increases risk of negative physical health outcomes associated with obesity. Across two nationally representative studies, we tested whether past obesity is associated with current psychological outcomes and whether these psychological outcomes explain the association between past obesity and subsequent early mortality.

Methods: Data were from the National Health and Nutrition Examination Survey (NHANES) (n = 29,047) and the Health and Retirement Study (HRS) (n = 11,998). Past obesity was defined based on maximum lifetime weight in NHANES and the highest weight from past study waves in the HRS. Across both studies, current depressive symptoms were analysed. A set of 10 additional well-being measures were combined to produce an 'index of impaired well-being' in HRS. Subsequent all-cause mortality was examined using National Deaths Index records in NHANES and household interviews in HRS. Linear or logistic regression, Cox proportional hazard regression, and causal mediation models were used.

Results: We found that past obesity was associated with greater current depressive symptoms after controlling for current weight status and in analyses limited to those who were no longer classified as having obesity in NHANES (β = 0.17; 95% CI: 0.13, 0.22) and HRS (β = 0.20; 95% CI: 0.08, 0.31). In HRS, past obesity was also associated with a range of current negative psychological outcomes, including an index of impaired psychological well-being (β = 0.16; 95% CI: 0.05, 0.27). Past obesity was associated with a higher risk of early mortality in both NHANES and HRS (HR = 1.31; 95% CI: 1.16, 1.48 and HR = 1.34; 95% CI: 1.20, 1.50, respectively). Depressive symptoms explained 6% (95% CI: 0.01, 0.10) and 5% (95% CI: 0.01, 0.09) of the association between past obesity and premature mortality in NHANES and HRS, respectively. Impaired psychological well-being partly mediated the association between past obesity and premature mortality by 10% (95% CI: 0.04, 0.16) in HRS.

Conclusions: Our findings suggest that there may be a psychological legacy of past obesity that is associated with raised mortality risk. Ensuring people with obesity receive psychological support even after experiencing weight loss may be important.

Titel:	The psychological legacy of past obesity and early mortality: evidence from two longitudinal studies.
Autor/in / Beteiligte Person:	Putra, IGNE ; Daly, M ; Sutin, A ; Steptoe, A ; Robinson, E
Link:	Full Text Finder (Volltext)
Zeitschrift:	BMC medicine, Jg. 21 (2023-11-16), Heft 1, S. 448
Veröffentlichung:	[London] : BioMed Central, 2003-, 2023
Medientyp:	academicJournal
ISSN:	1741-7015 (electronic)
DOI:	10.1186/s12916-023-03148-3
Schlagwort:	Humans Nutrition Surveys Longitudinal Studies Weight Loss Risk Factors Obesity complications Overweight complications
Sonstiges:	Nachgewiesen in: MEDLINE Sprachen: English Publication Type: Journal Article Language: English [BMC Med] 2023 Nov 16; Vol. 21 (1), pp. 448. <i>Date of Electronic Publication: </i>2023 Nov 16. MeSH Terms: Obesity* / complications ; Overweight* / complications ; Humans ; Nutrition Surveys ; Longitudinal Studies ; Weight Loss ; Risk Factors References: Arch Gen Psychiatry. 2010 Mar;67(3):220-9. (PMID: 20194822) ; SSM Popul Health. 2021 Feb 17;13:100755. (PMID: 33718581) ; Prev Med. 2018 Mar;108:47-52. (PMID: 29277416) ; BMC Public Health. 2022 Aug 20;22(1):1585. (PMID: 35987999) ; BMC Med. 2018 Jul 20;16(1):112. (PMID: 30025524) ; JAMA Netw Open. 2018 Nov 2;1(7):e183788. (PMID: 30646365) ; PLoS One. 2020 Sep 11;15(9):e0239004. (PMID: 32915921) ; Public Health Nutr. 2016 Aug;19(12):2106-21. (PMID: 26714776) ; Am J Prev Med. 2019 Feb;56(2):241-250. (PMID: 30661572) ; Int J Obes (Lond). 2009 Mar;33(3):335-41. (PMID: 19139752) ; Int J Geriatr Psychiatry. 2020 Jan;35(1):29-36. 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The psychological legacy of past obesity and early mortality: evidence from two longitudinal studies.