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Salidroside directly activates HSC70, revealing a new role for HSC70 in BDNF signalling and neurogenesis after cerebral ischemia.

Lai, W ; Luo, R ; et al.
In: Phytotherapy research : PTR, Jg. 38 (2024-06-01), Heft 6, S. 2619-2640
Online academicJournal

Titel:
Salidroside directly activates HSC70, revealing a new role for HSC70 in BDNF signalling and neurogenesis after cerebral ischemia.
Autor/in / Beteiligte Person: Lai, W ; Luo, R ; Tang, Y ; Yu, Z ; Zhou, B ; Yang, Z ; Brown, J ; Hong, G
Link:
Zeitschrift: Phytotherapy research : PTR, Jg. 38 (2024-06-01), Heft 6, S. 2619-2640
Veröffentlichung: <June 1990-> : Chichester : Wiley ; <i>Original Publication</i>: London : Heyden & Son, c1987-, 2024
Medientyp: academicJournal
ISSN: 1099-1573 (electronic)
DOI: 10.1002/ptr.8178
Schlagwort:
  • Animals
  • Rats
  • Male
  • Doublecortin Protein
  • Rhodiola chemistry
  • Receptor, trkB metabolism
  • Disease Models, Animal
  • Azepines
  • Benzamides
  • Phenols pharmacology
  • Phenols chemistry
  • Glucosides pharmacology
  • Neurogenesis drug effects
  • Brain-Derived Neurotrophic Factor metabolism
  • Infarction, Middle Cerebral Artery drug therapy
  • Neuroprotective Agents pharmacology
  • Neuroprotective Agents chemistry
  • Rats, Sprague-Dawley
  • Brain Ischemia drug therapy
  • HSC70 Heat-Shock Proteins metabolism
  • Signal Transduction drug effects
Sonstiges:
  • Nachgewiesen in: MEDLINE
  • Sprachen: English
  • Publication Type: Journal Article
  • Language: English
  • [Phytother Res] 2024 Jun; Vol. 38 (6), pp. 2619-2640. <i>Date of Electronic Publication: </i>2024 Mar 15.
  • MeSH Terms: Phenols* / pharmacology ; Phenols* / chemistry ; Glucosides* / pharmacology ; Neurogenesis* / drug effects ; Brain-Derived Neurotrophic Factor* / metabolism ; Infarction, Middle Cerebral Artery* / drug therapy ; Neuroprotective Agents* / pharmacology ; Neuroprotective Agents* / chemistry ; Rats, Sprague-Dawley* ; Brain Ischemia* / drug therapy ; HSC70 Heat-Shock Proteins* / metabolism ; Signal Transduction* / drug effects ; Animals ; Rats ; Male ; Doublecortin Protein ; Rhodiola / chemistry ; Receptor, trkB / metabolism ; Disease Models, Animal ; Azepines ; Benzamides
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  • Grant Information: 81973503 National Natural Science Foundation of China; 82174001 National Natural Science Foundation of China; 2019J01345 Natural Science Foundation of Fujian Province, China; 2020J01727 Natural Science Foundation of Fujian Province, China; 2021J02014 Natural Science Foundation of Fujian Province, China
  • Contributed Indexing: Keywords: BDNF; Rhodiola crenulata; heat shock cognate 71‐kDa protein; neurogenesis; salidroside; stroke
  • Substance Nomenclature: M983H6N1S9 (rhodioloside) ; 0 (Phenols) ; 0 (Glucosides) ; 0 (Brain-Derived Neurotrophic Factor) ; 0 (Neuroprotective Agents) ; 0 (Bdnf protein, rat) ; 0 (HSC70 Heat-Shock Proteins) ; 0 (Dcx protein, rat) ; 0 (Doublecortin Protein) ; EC 2.7.10.1 (Receptor, trkB) ; 0 (ANA 12 compound) ; 0 (Azepines) ; 0 (Benzamides)
  • Entry Date(s): Date Created: 20240315 Date Completed: 20240612 Latest Revision: 20240612
  • Update Code: 20240612

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