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Bariatric surgery is an effective treatment for severe obesity, but complications and peri-operative monitoring are important considerations. We conducted a comprehensive review of studies assessing pre-operative biomarkers and complications in patients undergoing bariatric surgery. A total of 14 studies were included. Gastric leak, infections, bleeding, obstruction or stenosis, hypoglycemia, and hypoalbuminemia were the most common complications observed. Our analysis showed a significant association between lower pre-operative albumin levels and complications (SMD [95%CI] = - 0.21 [- 0.38; - 0.04]). However, other biomarkers did not have a significant impact on complication occurrence. Changes in C-reactive protein, neutrophil-lymphocyte ratio, and white blood cell levels were observed in certain peri-operative time points and complication subgroups. These findings suggest the potential use of pre-operative biomarkers and peri-operative changes of biomarker's levels for predicting complications.

Titel:	Periprocedural Changes of Serum Biomarkers in Predicting Complications Following Bariatric Surgery for Obesity: Systematic Review and Meta-analysis.
Autor/in / Beteiligte Person:	AziziKia, H ; Shojaei, S ; Mousavi, A ; Salabat, D ; Shaker, F ; Dolama, RH ; Radkhah, H ; Alilou, S
Link:	Full Text Finder (Volltext)
Zeitschrift:	Obesity surgery, Jg. 34 (2024-06-01), Heft 6, S. 2198-2215
Veröffentlichung:	2006- : New York : Springer Science + Business Media ; <i>Original Publication</i>: Oxford, OX, UK : Rapid Communications of Oxford, [1991-, 2024
Medientyp:	academicJournal
ISSN:	1708-0428 (electronic)
DOI:	10.1007/s11695-024-07234-0
Schlagwort:	Humans C-Reactive Protein analysis C-Reactive Protein metabolism Female Predictive Value of Tests Biomarkers blood Bariatric Surgery adverse effects Postoperative Complications blood Postoperative Complications etiology Obesity, Morbid surgery Obesity, Morbid blood Obesity, Morbid complications
Sonstiges:	Nachgewiesen in: MEDLINE Sprachen: English Publication Type: Systematic Review; Journal Article; Meta-Analysis; Review Language: English [Obes Surg] 2024 Jun; Vol. 34 (6), pp. 2198-2215. <i>Date of Electronic Publication: </i>2024 Apr 27. MeSH Terms: Biomarkers* / blood ; Bariatric Surgery* / adverse effects ; Postoperative Complications* / blood ; Postoperative Complications* / etiology ; Obesity, Morbid* / surgery ; Obesity, Morbid* / blood ; Obesity, Morbid* / complications ; Humans ; C-Reactive Protein / analysis ; C-Reactive Protein / metabolism ; Female ; Predictive Value of Tests References: Gloy V, Briel M, Bhatt DL, et al. Bariatric surgery versus non-surgical treatment for obesity: a systematic review and meta-analysis of randomised controlled trials. 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(PMID: 2523402110.1245/s10434-014-4096-5) ; JC Kim MG Kim JK Park 2023 Outcomes and adverse events after bariatric surgery: an updated systematic review and meta-analysis, 2013–2023 J Metab Bariatr Surg 12 2 76 88. (PMID: 381967851077197010.17476/jmbs.2023.12.2.76) Contributed Indexing: Keywords: Bariatric surgery; CBC biomarkers; Complications; Inflammatory biomarkers Substance Nomenclature: 0 (Biomarkers) ; 9007-41-4 (C-Reactive Protein) Entry Date(s): Date Created: 20240427 Date Completed: 20240525 Latest Revision: 20240613 Update Code: 20240614

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Periprocedural Changes of Serum Biomarkers in Predicting Complications Following Bariatric Surgery for Obesity: Systematic Review and Meta-analysis.