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Discovering Inflammation in Atherosclerosis: Insights from Pathogenic Pathways to Clinical Practice.

Madaudo, C ; Coppola, G ; et al.
In: International journal of molecular sciences, Jg. 25 (2024-05-30), Heft 11
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This comprehensive review explores the various scenarios of atherosclerosis, a systemic and chronic arterial disease that underlies most cardiovascular disorders. Starting from an overview of its insidious development, often asymptomatic until it reaches advanced stages, the review delves into the pathophysiological evolution of atherosclerotic lesions, highlighting the central role of inflammation. Insights into clinical manifestations, including heart attacks and strokes, highlight the disease's significant burden on global health. Emphasis is placed on carotid atherosclerosis, clarifying its epidemiology, clinical implications, and association with cognitive decline. Prevention strategies, lifestyle modifications, risk factor management, and nuanced antithrombotic treatment considerations are critical to managing cardiovascular complications, thus addressing a crucial aspect of cardiovascular health.

Titel:
Discovering Inflammation in Atherosclerosis: Insights from Pathogenic Pathways to Clinical Practice.
Autor/in / Beteiligte Person: Madaudo, C ; Coppola, G ; Parlati, ALM ; Corrado, E
Link:
Zeitschrift: International journal of molecular sciences, Jg. 25 (2024-05-30), Heft 11
Veröffentlichung: Basel, Switzerland : MDPI, [2000-, 2024
Medientyp: academicJournal
ISSN: 1422-0067 (electronic)
DOI: 10.3390/ijms25116016
Schlagwort:
  • Humans
  • Risk Factors
  • Animals
  • Atherosclerosis pathology
  • Atherosclerosis metabolism
  • Inflammation pathology
Sonstiges:
  • Nachgewiesen in: MEDLINE
  • Sprachen: English
  • Publication Type: Journal Article; Review
  • Language: English
  • [Int J Mol Sci] 2024 May 30; Vol. 25 (11). <i>Date of Electronic Publication: </i>2024 May 30.
  • MeSH Terms: Atherosclerosis* / pathology ; Atherosclerosis* / metabolism ; Inflammation* / pathology ; Humans ; Risk Factors ; Animals
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  • Contributed Indexing: Keywords: atherosclerosis; cardiovascular disease; carotid atherosclerosis; cerebrovascular disease; inflammation; preventive cardiology
  • Entry Date(s): Date Created: 20240619 Date Completed: 20240619 Latest Revision: 20240625
  • Update Code: 20240625
  • PubMed Central ID: PMC11173271

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