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A novel <superscript>99m</superscript>Tc labelling strategy for the development of silica based particles for medical applications.
In: Dalton Transactions: An International Journal of Inorganic Chemistry, Jg. 43 (2014-03-18), Heft 11, S. 4260-4263
Online
academicJournal
Zugriff:
The reaction of high-valent fac-{ 99m TcO 3 } + complexes with alkenes ((3 + 2)-cycloaddition) has been used to develop a novel labelling procedure for silica based particles. This strategy can help to gain more detailed in vivo data of mesoporous silica by non-invasive radioimaging in the future. By applying norbornene as a coupling unit the (3 + 2)-cycloaddition reaction proceeds stereoselectively and with high reaction rates. [ABSTRACT FROM AUTHOR]
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Titel: |
A novel <superscript>99m</superscript>Tc labelling strategy for the development of silica based particles for medical applications.
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Autor/in / Beteiligte Person: | Wuillemin, Michel A. ; Stuber, Wanda T. ; Fox, Thomas ; Reber, Michael J. ; Brühwiler, Dominik ; Alberto, Roger ; Braband, Henrik |
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Zeitschrift: | Dalton Transactions: An International Journal of Inorganic Chemistry, Jg. 43 (2014-03-18), Heft 11, S. 4260-4263 |
Veröffentlichung: | 2014 |
Medientyp: | academicJournal |
ISSN: | 1477-9226 (print) |
DOI: | 10.1039/c3dt53019a |
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