Web-based collaborative care intervention to manage cancer-related symptoms in the palliative care setting.
In: Cancer (0008543X), Jg. 122 (2016-04-15), Heft 8, S. 1270-1282
Online
academicJournal
Zugriff:
Background: The aim of this study was to examine the efficacy of a collaborative care intervention in reducing depression, pain, and fatigue and improve quality of life. Methods: A total of 261 patients with advanced cancer and 179 family caregivers were randomized to a web-based collaborative care intervention or enhanced usual care. The intervention included the following: 1) a web site with written and audiovisual self-management strategies, a bulletin board, and other resources; 2) visits with a care coordinator during a physician's appointment every 2 months; and 3) telephone follow-up every 2 weeks. Primary patient outcomes included measures of depression, pain, fatigue, and health-related quality of life. Secondary outcomes included Interleukin (IL)-1α, IL-1β, IL-6, and IL-8 levels, Natural Killer (NK) cell numbers, and caregiver stress and depression. Results: At the baseline, 51% of the patients reported 1 or more symptoms in the clinical range. For patients who presented with clinical levels of symptoms and were randomized to the intervention, reductions in depression (Cohen's d = 0.71), pain (Cohen's d = 0.62), and fatigue (Cohen's d = 0.26) and improvements in quality of life (Cohen's d = 0.99) were observed when compared to those in the enhanced usual car arm at 6 months. Reductions in IL-6 (φ = 0.18), IL-1β (φ = 0.35), IL-1α (φ = 0.19), and IL-8 (φ = 0.15) and increases in NK cell numbers (φ = 0.23) were observed in comparison with enhanced usual care arm at 6 months. Reductions in caregiver stress (Cohen's d = 0.75) and depression (Cohen's d = 0.37) were observed at 6 months for caregivers whose loved ones were randomized to the intervention arm. Conclusions: The integration of screening and symptom management into cancer care is recommended. [ABSTRACT FROM AUTHOR]
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Web-based collaborative care intervention to manage cancer-related symptoms in the palliative care setting.
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Autor/in / Beteiligte Person: | Steel, Jennifer L. ; Geller, David A. ; Kim, Kevin H. ; Butterfield, Lisa H. ; Spring, Michael ; Grady, Jonathan ; Sun, Weiing ; Marsh, Wallis ; Antoni, Michael ; Dew, Mary Amanda ; Helgeson, Vicki ; Schulz, Richard ; Tsung, Allan |
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Zeitschrift: | Cancer (0008543X), Jg. 122 (2016-04-15), Heft 8, S. 1270-1282 |
Veröffentlichung: | 2016 |
Medientyp: | academicJournal |
ISSN: | 0008-543X (print) |
DOI: | 10.1002/cncr.29906 |
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