Safe and successful birth following pelvic radiotherapy for rectal mucosa-associated lymphoid tissue lymphoma: a case report.
In: Journal of Medical Case Reports, Jg. 11 (2017-02-01), S. 1-5
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Zugriff:
Background: Mucosa-associated lymphoid tissue lymphomas can occur in various parts of the body, and half of mucosa-associated lymphoid tissue lymphomas occur in the gastrointestinal tract. Gastric mucosa-associated lymphoid tissue lymphoma is the most common lymphoma of the gastrointestinal tract and primary rectal mucosa-associated lymphoid tissue lymphoma is very rare. Because of the high radiosensitivity of mucosa-associated lymphoid tissue lymphomas, this condition can be controlled with radiotherapy of approximately 30 Gy alone. However, ovarian dysfunction as an adverse event of radiotherapy for pelvic lesions can become a problem in girls and women. We report a case of a 28-year-old woman with rectal mucosa-associated lymphoid tissue lymphoma who safely gave birth to a baby following 30.6 Gy radiotherapy to her whole rectum. Case Presentation: A 28-year-old Japanese woman became aware of bloody stools and was diagnosed as having Lugano I rectal mucosa-associated lymphoid tissue lymphoma. She was referred to our institute and initiated on radiotherapy. However, she expressed a desire to bear children. We used horizontally opposed pair fields for radiotherapy to minimize the irradiation to her endometrium and ovary. A total dose of 30.6 Gy was given in 17 fractions of 1.8 Gy by 10-Megavolt X-ray linear accelerator. As a result, one-third of her uterus and half of her ovary were outside the irradiation field. After approximately 1 year of treatment, positive pregnancy was confirmed and finally she safely gave birth to a baby girl without congenital abnormalities. Conclusions: This report provides hope for girls and women who have undergone irradiation for pelvic mucosa-associated lymphoid tissue lymphomas and who desire to bear children. [ABSTRACT FROM AUTHOR]
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Safe and successful birth following pelvic radiotherapy for rectal mucosa-associated lymphoid tissue lymphoma: a case report.
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Autor/in / Beteiligte Person: | Hatayama, Yoshiomi ; Aoki, Masahiko ; Kawaguchi, Hideo ; Hirose, Katsumi ; Sato, Mariko ; Akimoto, Hiroyoshi ; Tanaka, Mitsuki ; Fujioka, Ichitaro ; Ono, Shuichi ; Takai, Yoshihiro |
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Zeitschrift: | Journal of Medical Case Reports, Jg. 11 (2017-02-01), S. 1-5 |
Veröffentlichung: | 2017 |
Medientyp: | academicJournal |
ISSN: | 1752-1947 (print) |
DOI: | 10.1186/s13256-016-1193-z |
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