The effect of chronic exercise on a biomarker of bone resorption in healthy adults.
In: Family Medicine & Primary Care Review, Jg. 21 (2019-07-01), Heft 3, S. 270-276
academicJournal
Zugriff:
Background. Long-term exercise contributes to the inhibition of osteoblast cell activity and to the decrease of bone resorption. Objectives. The research objective was to analyze the chronic effect of regular, long-term physical activity and physical inactivity on carboxyterminal collagen cross-linking telopeptide levels (CTx) and calcium levels in healthy adults. Material and methods. This study was a prospective cohort study. Fifty-four men and women, aged 17-26 years, were divided into 2 groups of 27 people each: exercise and non-exercise. This research was carried out from April 2015 to April 2016 at the Faculty of Medicine, Syiah Kuala University, Aceh, Indonesia. Bone resorption can be determined by measuring the carboxyterminal cross-linking telopeptide of collagen (CTx). The data were analyzed using Student's t-test and regression correlation analysis with a significance level of 5%. Results. The highest levels of CTx were found in the non-exercise group; the lowest levels of CTx were in the exercise group (1.6 ng/mL and 0.30 ng/mL, respectively). This difference in CTx levels between groups was statistically significant (0.52 ± 0.22 ng/mL vs 0.72 ± 0.28 ng/mL; p = 0.005). Calcium was significantly higher in the exercise group than in the non-exercise one (9.67 ± 0.30 vs 9.01 ± 0.21 mg/dl; p = 0.006). There was a negative correlation between calcium levels and CTx in the exercise group (r = 0.038; p = 0.001). Conclusions. Regular exercise led to lower CTx levels and increased calcium levels. The increase in calcium is an effect of the decrease in CTx in healthy adults. Regular exercise decreases bone resorption and increases bone calcium deposition in healthy adults. Regular exercise has the potential to prevent and treat osteoporosis non-pharmacologically. [ABSTRACT FROM AUTHOR]
Copyright of Family Medicine & Primary Care Review is the property of Termedia Publishing House and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
Titel: |
The effect of chronic exercise on a biomarker of bone resorption in healthy adults.
|
---|---|
Autor/in / Beteiligte Person: | YUSNI, YUSNI ; RAHMAN, SAFRIZAL |
Zeitschrift: | Family Medicine & Primary Care Review, Jg. 21 (2019-07-01), Heft 3, S. 270-276 |
Veröffentlichung: | 2019 |
Medientyp: | academicJournal |
ISSN: | 1734-3402 (print) |
DOI: | 10.5114/fmpcr.2019.88387 |
Schlagwort: |
|
Sonstiges: |
|