Analysis of Epidemiological and Clinical Features in Older Patients With Coronavirus Disease 2019 (COVID-19) Outside Wuhan.
In: Clinical Infectious Diseases, Jg. 71 (2020-08-15), Heft 15, S. 740-747
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Zugriff:
Background The outbreak of coronavirus disease 2019 (COVID-19) has become a large threat to public health in China, with high contagious capacity and varied mortality. This study aimed to investigate the epidemiological and clinical characteristics of older patients with COVID-19 outside Wuhan. Methods A retrospective study was performed, with collecting data from medical records of confirmed COVID-19 patients in Zhejiang province from 17 January to 12 February 2020. Epidemiological, clinical, and treatment data were analyzed between older (≥ 60 years) and younger (< 60 years) patients. Results A total of 788 patients with confirmed COVID-19 were selected; 136 were older patients with corresponding mean age of 68.28 ± 7.31 years. There was a significantly higher frequency of women in older patient group compared with younger patients (57.35% vs 46.47%, P = .021). The presence of coexisting medical conditions was significantly higher in older patients compared with younger patients (55.15% vs 21.93%, P < .001), including the rate of hypertension, diabetes, heart disease, and chronic obstructive pulmonary disease. Significantly higher rates of severe clinical type (older vs younger groups: 16.18% vs 5.98%, P < .001), critical clinical type (8.82% vs 0.77%, P < .001), shortness of breath (12.50% vs 3.07%, P < .001), and temperature of > 39.0°C (13.97% vs 7.21%, P = .010) were observed in older patients compared with younger patients. Finally, higher rates of intensive care unit admission (9.56% vs 1.38%, P < .001) and methylprednisolone application (28.68% vs 9.36%, P < .001) were also identified in older patients compared with younger ones. Conclusions The specific epidemiological and clinical features of older COVID-19 patients included significantly higher female sex, body temperature, comorbidities, and rate of severe and critical type disease. [ABSTRACT FROM AUTHOR]
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Analysis of Epidemiological and Clinical Features in Older Patients With Coronavirus Disease 2019 (COVID-19) Outside Wuhan.
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Autor/in / Beteiligte Person: | Lian, Jiangshan ; Jin, Xi ; Hao, Shaorui ; Cai, Huan ; Zhang, Shanyan ; Zheng, Lin ; Jia, Hongyu ; Hu, Jianhua ; Gao, Jianguo ; Zhang, Yimin ; Zhang, Xiaoli ; Yu, Guodong ; Wang, Xiaoyan ; Gu, Jueqing ; Ye, Chanyuan ; Jin, Ciliang ; Lu, Yingfeng ; Yu, Xia ; Yu, Xiaopeng ; Ren, Yue |
Zeitschrift: | Clinical Infectious Diseases, Jg. 71 (2020-08-15), Heft 15, S. 740-747 |
Veröffentlichung: | 2020 |
Medientyp: | academicJournal |
ISSN: | 1058-4838 (print) |
DOI: | 10.1093/cid/ciaa242 |
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