Postmortem Lung Findings in a Patient With Asthma and Coronavirus Disease 2019.
In: CHEST, Jg. 158 (2020-09-01), Heft 3, S. e99- (3S.)
academicJournal
Zugriff:
Asthma is increasingly recognized as an underlying risk factor for severe respiratory disease in patients with coronavirus disease 2019 (COVID-19), particularly in the United States. Here, we report the postmortem lung findings from a 37-year-old man with asthma, who met the clinical criteria for severe acute respiratory distress syndrome and died of COVID-19 less than 2 weeks after presentation to the hospital. His lungs showed mucus plugging and other histologic changes attributable to asthma, as well as early diffuse alveolar damage and a fibrinous pneumonia. The presence of diffuse alveolar damage is similar to descriptions of autopsy lung findings from patients with severe acute respiratory syndrome coronavirus and Middle East respiratory syndrome coronavirus, and the absence of a neutrophil-rich acute bronchopneumonia differs from the histologic changes typical of influenza. The relative contribution of mucus plugging to his hypoxemia is unknown. [ABSTRACT FROM AUTHOR]
Copyright of CHEST is the property of American College of Chest Physicians and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
Titel: |
Postmortem Lung Findings in a Patient With Asthma and Coronavirus Disease 2019.
|
---|---|
Autor/in / Beteiligte Person: | Konopka, Kristine E. ; Wilson, Allecia ; Myers, Jeffrey L. |
Zeitschrift: | CHEST, Jg. 158 (2020-09-01), Heft 3, S. e99- (3S.) |
Veröffentlichung: | 2020 |
Medientyp: | academicJournal |
ISSN: | 0012-3692 (print) |
DOI: | 10.1016/j.chest.2020.04.032 |
Schlagwort: |
|
Sonstiges: |
|