Systemic Immune-Inflammation Index Is a Predictor of Contrast-Induced Nephropathy in Patients With ST-Segment Elevation Myocardial Infarction.
In: Angiology, Jg. 73 (2022-02-01), Heft 2, S. 125-131
Online
academicJournal
Zugriff:
We evaluated the predictive value of admission systemic immune-inflammation index (SII) for the risk of contrast-induced nephropathy (CIN) in patients with ST-segment elevation myocardial infarction (STEMI) treated with primary percutaneous coronary intervention (pPCI). The neutrophil-to-lymphocyte ratio (NLR), platelet-to-lymphocyte ratio (PLR), and SII (platelet × NLR) levels were calculated in 1621 consecutive patients with STEMI. The relationship of these parameters with CIN development within 72 hours of pPCI was analyzed. Of the study population, 343 (21.1%) cases developed CIN. The frequency of CIN was 11.1% in the first SII quartile, 11.6% in the second SII quartile, 26.8% in the third SII quartile, and 35% in the fourth SII quartile, which differed significantly between groups (P <.01). Age, baseline glomerular filtration rate, contrast media volume, hypertension, C-reactive protein levels, and the quartiles of SII were independent predictors of CIN. Patients in the third SII quartile versus first SII quartile (OR: 2.906, 95% CI, 1.903-4.437; P <.001), and fourth SII quartile versus first SII quartile (OR: 4.168, 95% CI, 2.754-6.313; P <.001) had a significantly higher risk for CIN in the multivariable model. The SII may be a promising inflammatory parameter to predict CIN after pPCI. [ABSTRACT FROM AUTHOR]
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Titel: |
Systemic Immune-Inflammation Index Is a Predictor of Contrast-Induced Nephropathy in Patients With ST-Segment Elevation Myocardial Infarction.
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Autor/in / Beteiligte Person: | Öztürk, Recep ; İnan, Duygu ; Güngör, Barış |
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Zeitschrift: | Angiology, Jg. 73 (2022-02-01), Heft 2, S. 125-131 |
Veröffentlichung: | 2022 |
Medientyp: | academicJournal |
ISSN: | 0003-3197 (print) |
DOI: | 10.1177/00033197211029094 |
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