COVID-19 in Renal Transplant Recipients -- A Single Center Experience from India.
In: Indian Journal of Nephrology, Jg. 32 (2022-09-01), Heft 5, S. 416-422
Online
academicJournal
Zugriff:
Introduction: The information on the clinical outcome of renal transplant recipients getting COVID-19 infection is sparse. The aim of this study is to report a single-center experience of renal transplant recipients with COVID-19 from India. Methods: This was a retrospective study of 23 consecutive renal transplant recipients with COVID-19 infection presenting to our center from May 2020 to August 2020. Clinical parameters, laboratory values, imaging characteristics, and outcome of the patients were collected and analyzed. Results: Median follow-up duration was 36 (range: 10--110) days. Median age of patients was 54 (23--70) years, and 87% were male. Median duration since transplant was 69 (range: 15--132) months. The most common presenting feature was fever (82.6%), followed by breathlessness (43.5%) and cough (30.4%). Hospitalization rate was 52.2%, while 34.8% required ICU care. Severe to critical disease was seen in 39.1% of patients, and 17.4% required mechanical ventilation. Patients with severe disease had a higher incidence of lymphopenia (P = 0.005) when compared to the ones with mild to moderate disease. Acute kidney injury was seen in 39.1% of patients, and 13% required dialysis. Mortality rate was 13% overall, and 25% in those hospitalized. Conclusion: Renal transplant recipients with COVID-19 have a poor outcome. Although not all of them need hospitalization, they should be monitored closely. Immunosuppression minimization is an important part of the treatment strategy. [ABSTRACT FROM AUTHOR]
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COVID-19 in Renal Transplant Recipients -- A Single Center Experience from India.
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Autor/in / Beteiligte Person: | Jha, Pranaw Kumar ; Shukla, Saurabh ; Bansal, Dinesh ; Bansal, Shyam Bihari ; Sethi, Sidharth ; Jain, Manish ; Yadav, Dinesh Kumar ; Gadde, Ashwini ; Mahapatra, Amit Kumar ; Sodhi, Puneet ; Kher, Vijay |
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Zeitschrift: | Indian Journal of Nephrology, Jg. 32 (2022-09-01), Heft 5, S. 416-422 |
Veröffentlichung: | 2022 |
Medientyp: | academicJournal |
ISSN: | 0971-4065 (print) |
DOI: | 10.4103/ijn.IJN_479_20 |
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