Regional differences in utilization of 17α-hydroxyprogesterone caproate (17-OHP).
In: Journal of Perinatal Medicine, Jg. 50 (2022-11-01), Heft 9, S. 1203-1209
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Zugriff:
To describe regional differences in utilization of 17α-hydroxyprogesterone caproate (17-OHP). Retrospective cohort study of a large, US commercial managed care plan claims database with pharmacy coverage from 2008 to 2018. Singleton pregnancies with at least one prior spontaneous preterm birth (sPTB) were included. Regional and state-based differences in 17-OHP use were compared. Data were analyzed using t-tests and Fisher's exact tests. Of the 4,514 individuals with an indication for 17-OHP, 580 (12.8%) were prescribed 17-OHP. Regional and state-based differences in 17-OHP utilization were identified; Northeast 15.7%, Midwest 13.7%, South 12.0%, and West 10.4% (p=0.003). While significant regional differences in 17-OHP utilization were demonstrated, 17-OHP utilization remained low despite this cohort having insurance through a US commercial managed care plan. Suboptimal utilization demonstrates a disconnect between research and uptake in clinical practice. This underscores a need for implementation science in obstetrics to translate updated recommendations more effectively and efficiently into clinical practice. [ABSTRACT FROM AUTHOR]
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Titel: |
Regional differences in utilization of 17α-hydroxyprogesterone caproate (17-OHP).
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Autor/in / Beteiligte Person: | Hart, Jessica M. ; Hakim, Joe B. ; Wylie, Blair J. ; Beam, Andrew L. |
Zeitschrift: | Journal of Perinatal Medicine, Jg. 50 (2022-11-01), Heft 9, S. 1203-1209 |
Veröffentlichung: | 2022 |
Medientyp: | academicJournal |
ISSN: | 0300-5577 (print) |
DOI: | 10.1515/jpm-2021-0586 |
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