Reports Outline Colon Cancer Study Findings from University of Konstanz (Immune Escape of Colorectal Tumours Via Local Lrh-1/cyp11b1-mediated Synthesis of Immunosuppressive Glucocorticoids).
In: Gastroenterology Week, 2023-04-18, S. 773-773
serialPeriodical
Zugriff:
In established tumours, however, tumour-autonomous Cyp11b1-mediated glucocorticoid synthesis suppresses anti-tumour immune responses and promotes immune escape. Keywords: Constance; Germany; Europe; Adrenal Cortex Hormones; Cancer; Colon Cancer; Colorectal Research; Drugs and Therapies; Gastroenterology; Glucocorticoid Therapy; Glucocorticoids; Health and Medicine; Hormones; Inflammation; Oncology; Pharmaceuticals EN Constance Germany Europe Adrenal Cortex Hormones Cancer Colon Cancer Colorectal Research Drugs and Therapies Gastroenterology Glucocorticoid Therapy Glucocorticoids Health and Medicine Hormones Inflammation Oncology Pharmaceuticals 773 773 1 04/17/23 20230418 NES 230418 2023 APR 17 (NewsRx) -- By a News Reporter-Staff News Editor at Gastroenterology Week -- A new study on Oncology - Colon Cancer is now available. Transplantation of glucocorticoid synthesis-proficient colorectal tumour organoids into immunocompetent recipient mice resulted in rapid tumour growth, whereas transplantation of Cyp11b1-deleted and glucocorticoid synthesis-deficient tumour organoids was characterized by reduced tumour growth and increased immune cell infiltration. [Extracted from the article]
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Reports Outline Colon Cancer Study Findings from University of Konstanz (Immune Escape of Colorectal Tumours Via Local Lrh-1/cyp11b1-mediated Synthesis of Immunosuppressive Glucocorticoids).
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Zeitschrift: | Gastroenterology Week, 2023-04-18, S. 773-773 |
Veröffentlichung: | 2023 |
Medientyp: | serialPeriodical |
ISSN: | 1543-6756 (print) |
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