老年高血压患者衰弱患病率的meta分析. (Chinese)

Objective To investigate the prevalence of frailty in elderly hypertension patients by metaanalysis. Methods Chinese and foreign databases were searched from the construction of the library to May 10, 2022, including China National Knowledge Infrastructure(CNKI), Wanfang Database, VIP Journal Database, China Biomedical Literature Service System(CBM), PubMed, Cochrane Library, Embase, and Web of Science databases. Screening was performed according to the inclusion and exclusion criteria, the quality of the included literature was assessed, data were extracted, and the Stata 17. 0 software was used for meta-analysis. Results A total of 46 articles were included, including 29 216 elderly patients with hypertension and 7 513 patients with frailty. The overall prevalence of frailty in elderly hypertension patients was 32% [95% confidence interval(95%CI):27-36], and the prevalence of pre-frailty in elderly hypertension patients was 50%(95% CI:42-58), the prevalence of male frailty in elderly patients with hypertension was 15%(95%CI:12-18), and the prevalence of female frailty in elderly patients with hypertension was 14%(95%CI:11-17). The prevalence of frailty diagnosed by different assessment tools from high to low was respectively the comprehensive frailty assessment Instrument(59%), the tilburg frailty indicator(50%), the frailty index-20(44%), the kihon checklist(37%), comprehensive geriatric assessment(33%), the FRAIL scale(29%), clinical frailty scale (28%), frailty index(26%), the Fried frailty phenotype(23%) and 4mGait gait assessment method(20%). The prevalence of frailty in elderly hypertension patients among different countries: Poland(67%), South Korea( 29%), China(30%), Brazil(24%), Japan(24%) and United States(8%); prevalence of frailty in different years:2016(67%), 2019(43%), 2017(38%), 2022(38%), 2021(30%), 2020(28%), 2018(24%), 2015(23%) and 2014(10%). The prevalence of frailty among elderly hypertension patients in rural areas, elderly care institutions, health care units, community/inpatient settings, and inpatient/outpatient clinics was 16%, 19%, 44%, 17% and 17%, respectively. The prevalence of frailty in elderly hypertension patients diagnosed with Tilburg frailty Index was higher than that diagnosed with Fried frailty phenotype, and the prevalence of frailty in elderly hypertension patients hospitalized and community(37% and 32%, respectively) was higher than that in outpatient department(30%). Conclusion The available epidemiological evidence shows that elderly patients with hypertension have a high prevalence of frailty. [ABSTRACT FROM AUTHOR]

目的 通过meta分析了解老年高血压患者衰弱的患病情况。方法 检索中国知网(CNKI)、 万方医学网、维普资讯中文期刊服务平台、中国生物医学文献服务系统(CBM)、PubMed、Cochrane Library、 Embase、Web of Science等中、英文数据库中有关老年高血压与衰弱的研究,检索时限为建库至2022年5月10 日。按文献纳入、排除标准进行筛选,评估纳入文献质量,提取数据资料,应用Stata17.0软件进行meta分析。 结果 共纳入文献46篇,老年高血压患者29 216例,衰弱7 513例。老年高血压患者衰弱患病率为32%[95% 可信区间(95%CI):27~36],老年髙血压患者衰弱前期患病率为50%(95%CI:42~58),男性老年髙血压患者 衰弱患病率为15%(95%CI:12~18),女性为14%(95%CI:11~17)。不同评估工具诊断老年高血压患者衰弱 患病率由高至低分别为衰弱综合评估工具(59%)、蒂尔堡衰弱指标量表(50%)、临床功能脆弱性指数-20 (44%)、老年衰弱筛查量表(37%)、老年综合评估衰弱指数(33%)、衰弱评估量表(29%)、临床衰弱量表 (28%)、衰弱指数(26%)、Fried衰弱表型量表(23%)、4mGait步速评定方法(20%);不同国家老年高血压患者 衰弱患病率由高至低分别为波兰(67%)、韩国(29%)、中国(30%)、巴西(24%)、日本(24%)、美国(8%);不同 年份老年高血压患者衰弱患病率由高至低分别为2016年(67%)、2019 年(43%)、2017 年(38%)、2022 年 (38%)、2021年(30%)、2020年(28%)、2018年(24%)、2015年(23%)、2014年(10%);农村、养老机构、保健单 位、社区/住院、住院/门诊老年高血压患者衰弱患病率分别为16%、19%、44%、17%、17%;采用蒂尔堡衰弱指 标量表诊断老年高血压患者衰弱患病率高于Fried衰弱表型量表,住院和社区老年高血压患者衰弱患病率(分 别为37%、32%)均高于门诊(30%)。结论 现有流行病学证据表明老年高血压患者衰弱患病率较高。 [ABSTRACT FROM AUTHOR]

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