Η ανεκπλήρωτη ιατρική ανάγκη στη διαχείριση των ενηλίκων ασθενών με μέτρια έως σοβαρή ατοπική δερματίτιδα στην Ελλάδα (Greek, Ancient (to 1453))

Atopic dermatitis (AD) is a chronic relapsing, inflammatory skin disease with a significant impact on the quality of life of patients. The aim of this consensus was to investigate the unmet medical need in the management of adult patients suffering from moderate-to-severe AD in Greece. Initially, an extensive literature review was conducted on diagnosis, epidemiology, disease burden, treatments and AD guidelines to develop preliminary statements. In the second phase, these statements were validated, new ones were added when necessary, and finally, voted through the Delphi method by a consensus panel of medical experts-dermatologists. In the third and final phase, the validated statements were presented to a second consensus group of clinical expert-dermatologists for final vote and strengthening of the consensus. In total, 15 clinicians participated in the processes of formulation, validation and voting of 35 statements. In the final consensus, agreement rates ranged from 75% to 100% on 97.14% of the total statements. The prevalence and burden of moderate to severe AD is high, necessitating better therapeutic management of the disease. Therefore, there is an emerging need for new, more effective and safer treatment options in moderate to severe AD in Greece. New biological therapies and small molecules are supported by high efficacy and a favorable safety profile. The development of Greek guidelines and a therapeutic protocol, defining the prescribing framework for the new innovative therapies, would significantly contribute to the optimization of the disease management. [ABSTRACT FROM AUTHOR]

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