Study uncovers function of mysterious disordered regions of proteins implicated in cancer.
In: Clinical Oncology Week, 2023-10-17, S. 1230-1230
serialPeriodical
Zugriff:
Keywords: Cancer; Dana-Farber Cancer Institute; Genetics; Health and Medicine; Oncology; Peptides; Peptides and Proteins; Proteins EN Cancer Dana-Farber Cancer Institute Genetics Health and Medicine Oncology Peptides Peptides and Proteins Proteins 1230 1230 1 10/16/23 20231017 NES 231017 2023 OCT 17 (NewsRx) -- By a News Reporter-Staff News Editor at Clinical Oncology Week -- Study uncovers function of mysterious disordered regions of proteins implicated in cancer Study Title: A disordered region controls cBAF activity via condensation and partner recruitment Publication: Cell, Monday, October 2, 2023 (https://www.dana-farber.org/newsroom/news-releases/2023/study-uncovers-function-of-mysterious-disordered-regions-of-proteins-implicated-in-cancer/) Dana-Farber Cancer Institute author: Cigall Kadoch, PhD Summary: New research from Dana-Farber Cancer Institute researcher Cigall Kadoch, PhD, along with colleagues at Princeton University and the Washington University in St. Louis, reveals a key role for intrinsically disordered proteins known as IDRs that are implicated in a wide range of human diseases, from cancer to neurodegeneration. This study sheds light on the sequence-specific contributions of IDRs to the highly disease-relevant mSWI/SNF (BAF) chromatin remodeling complexes, which have become top therapeutic targets in oncology. [Extracted from the article]
Copyright of Clinical Oncology Week is the property of NewsRx and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
Titel: |
Study uncovers function of mysterious disordered regions of proteins implicated in cancer.
|
---|---|
Zeitschrift: | Clinical Oncology Week, 2023-10-17, S. 1230-1230 |
Veröffentlichung: | 2023 |
Medientyp: | serialPeriodical |
ISSN: | 1543-6799 (print) |
Schlagwort: |
|
Sonstiges: |
|