重型新型冠状病毒感染的临床与 CT 特征. (Chinese)

Objective: To retrospectively investigate the clinical manifestations and imaging features of heavy novel coronavirus pneumonia (NCP). Materials and methods: Fifty-two patients with positive chest computed tomography (CT) manifestations and a confirmed diagnosis of COVID-19 in the Infection Unit from November 2022 to January 2023 were included in our study. All patients underwent chest thin-section CT examination and had more complete clinical data from 1 to 14 days after onset. Patients were divided into two groups based on the time interval between onset and CT examination ( < 7 and ≥ 7 days), and the differences in CT performance characteristics between the two groups were compared. Results: Among the 52 patients with severe COVID-19, the age range was approximately 53 to 97 years, with a median age of 80 years in 4 men and 18 women. Thirty-three patients (63.5%) with underlying diseases were combined, including 2 (3.8%) with pulmonary disease, 6 (11.5%) with diabetes mellitus, 18 (34.6%) with hypertension, 16 (30.8%) with coronary heart disease, and 7 (13.5%) with cerebrovascular disease. The main symptoms of patients included fever in 44 (84.6%), cough in 43 (82.7%), myalgia in 2 (3.8%), sore throat in 19 (36.5%), chest tightness in 9 (17.3%), diarrhea in 2 (3.8%), and poor appetite in 3 (5.8%). The differences in lesion involvement and lesion size were statistically significant between patients grouped at the time interval between onset and CT examination. Conclusions: Severe COVID-19 is more common in older adult males, mostly combined with underlying disease. CT features include more airway involvement in the short term, and bloodway involvement is more common in those with longer onset. [ABSTRACT FROM AUTHOR]

目的：探讨重型新型冠状病毒感染 (COVID-19) 的临床表现及胸部 CT 平扫的影像学特征。材料与 方法：回顾性收集 2022 年 11 月至 2023年1 月确诊的重型 COVID-19 且胸部 CT 表现阳性的患者 52 例， 所有患者自发病后 1～14 d 行胸部薄层平扫 CT 检查和有较完整的临床资料。根据患者发病与 CT 检查的 时间间隔 ( < 7d 和 ≥ 7d) 将患者各分为两组，比较两组患者的 CT 平扫影像学特征的差异性。结果：52 例重型 COVID-19 患者中，年龄范围约 53～97 岁，中位年龄为 80 岁，男 34 例，女 18 例，且 33 例 (63.5％) 合并基础疾病，其中肺部疾病 2 例 (3.8％) ，糖尿病 6 例 (11.5％) 、高血压 18 例 (34.6％) 、 冠心病 16 例 (30.8％) 、脑血管疾病 7 例 (13.5％) 、恶性肿瘤 4 例 (7.7％) 、免疫疾病 4 例 (7.7％) ； 患者主要症状有发热 44 例 (84.6％) 、咳嗽 43 例 (82.7％) 、肌痛 2 例 (3.8％) 、咽痛 19 例 (36.5％) 、 胸闷 9 例 (17.3％) 、腹泻 2 例 (3.8％) 、纳差 3 例 (5.8％) 。发病与 CT 检查时间间隔分组患者之间， 病变累及部位、病变大小等 CT 表现特征差异有统计学意义。结论：重型 COVID-19 以老年男性多见，多 合并基础疾病，CT 特征为短期内多累及气管，发病时间较长者血管受累多见。 [ABSTRACT FROM AUTHOR]

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