Investigators at Translational Research Institute Report Findings in Gene Therapy (Aav-based Strategies for Treatment of Retinal and Choroidal Vascular Diseases: Advances In Age-related Macular Degeneration and Diabetic Retinopathy Therapies).
In: Gene Therapy Weekly, 2023-12-04, S. 360-360
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A report from the Translational Research Institute in Brisbane, Australia discusses the use of adeno-associated virus (AAV) as a vector for ocular gene delivery in the treatment of age-related macular degeneration (AMD) and diabetic retinopathy (DR). Current treatments for these vascular diseases are burdensome and have limitations, so there is a need for long-lasting alternatives with improved safety and efficacy. The report explores various strategies using AAV-mediated gene delivery, including engineered capsids, targeted expression, gene silencing, and editing. The report provides an overview of preclinical efficacy studies and the latest data from clinical trials for both diseases. [Extracted from the article]
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Investigators at Translational Research Institute Report Findings in Gene Therapy (Aav-based Strategies for Treatment of Retinal and Choroidal Vascular Diseases: Advances In Age-related Macular Degeneration and Diabetic Retinopathy Therapies).
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Zeitschrift: | Gene Therapy Weekly, 2023-12-04, S. 360-360 |
Veröffentlichung: | 2023 |
Medientyp: | serialPeriodical |
ISSN: | 1078-2842 (print) |
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