Advances in the study of IL-17 in neurological diseases and mental disorders.
In: Frontiers in Neurology, 2023-12-02, S. 1-16
Online
academicJournal
Zugriff:
Interleukin-17 (IL-17), a cytokine characteristically secreted by T helper 17 (Th17) cells, has attracted increasing attention in recent years because of its importance in the pathogenesis of many autoimmune or chronic inflammatory diseases. Recent studies have shown that neurological diseases and mental disorders are closely related to immune function, and varying degrees of immune dysregulation may disrupt normal expression of immune molecules at critical stages of neural development. Starting from relevant mechanisms affecting immune regulation, this article reviews the research progress of IL-17 in a selected group of neurological diseases and mental disorders (autism spectrum disorder, Alzheimer's disease, epilepsy, and depression) from the perspective of neuroinflammation and the microbiota-gut-brain axis, summarizes the commonalities, and provides a prospective outlook of target application in disease treatment. [ABSTRACT FROM AUTHOR]
Copyright of Frontiers in Neurology is the property of Frontiers Media S.A. and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
Titel: |
Advances in the study of IL-17 in neurological diseases and mental disorders.
|
---|---|
Autor/in / Beteiligte Person: | Lu, Yu ; Zhang, Piaopiao ; Xu, Fenfen ; Zheng, Yuan ; Zhao, Hongyang |
Link: | |
Zeitschrift: | Frontiers in Neurology, 2023-12-02, S. 1-16 |
Veröffentlichung: | 2023 |
Medientyp: | academicJournal |
ISSN: | 1664-2295 (print) |
DOI: | 10.3389/fneur.2023.1284304 |
Schlagwort: |
|
Sonstiges: |
|