DNA-functionalized metal or metal-containing nanoparticles for biological applications.
In: Dalton Transactions: An International Journal of Inorganic Chemistry, Jg. 53 (2024-01-21), Heft 3, S. 839-850
academicJournal
Zugriff:
The conjugation of DNA molecules with metal or metal-containing nanoparticles (M/MC NPs) has resulted in a number of new hybrid materials, enabling a diverse range of novel biological applications in nanomaterial assembly, biosensor development, and drug/gene delivery. In such materials, the molecular recognition, gene therapeutic, and structure-directing functions of DNA molecules are coupled with M/MC NPs. In turn, the M/MC NPs have optical, catalytic, pore structure, or photodynamic/photothermal properties, which are beneficial for sensing, theranostic, and drug loading applications. This review focuses on the different DNA functionalization protocols available for M/MC NPs, including gold NPs, upconversion NPs, metal–organic frameworks, metal oxide NPs and quantum dots. The biological applications of DNA-functionalized M/MC NPs in the treatment or diagnosis of cancers are discussed in detail. [ABSTRACT FROM AUTHOR]
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Titel: |
DNA-functionalized metal or metal-containing nanoparticles for biological applications.
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Autor/in / Beteiligte Person: | Liu, Bei ; Duan, Huijuan ; Liu, Zechao ; Liu, Yuechen ; Chu, Hongqian |
Zeitschrift: | Dalton Transactions: An International Journal of Inorganic Chemistry, Jg. 53 (2024-01-21), Heft 3, S. 839-850 |
Veröffentlichung: | 2024 |
Medientyp: | academicJournal |
ISSN: | 1477-9226 (print) |
DOI: | 10.1039/d3dt03614f |
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