Short-term social isolation acts on hypothalamic neurons to promote social behavior in a sex- and context-dependent manner (Updated January 17, 2024).
In: Mental Health Weekly Digest, 2024-02-02, S. 462-462
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Zugriff:
A preprint abstract from biorxiv.org discusses a study on the effects of short-term social isolation on social behavior in mice. The researchers identified a population of neurons in the preoptic hypothalamus that promote social behavior in single-housed female mice. Chemogenetic silencing of these neurons attenuated the effects of isolation on social investigation and vocalizations, while ablation of the neurons reduced mounting behavior. Similar results were observed in single-housed males, but the neurons were activated by opposite-sex interactions. The study suggests that these hypothalamic neurons play a role in promoting social behavior following short-term isolation in a sex- and social context-dependent manner. [Extracted from the article]
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Short-term social isolation acts on hypothalamic neurons to promote social behavior in a sex- and context-dependent manner (Updated January 17, 2024).
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Zeitschrift: | Mental Health Weekly Digest, 2024-02-02, S. 462-462 |
Veröffentlichung: | 2024 |
Medientyp: | serialPeriodical |
ISSN: | 1543-6616 (print) |
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