Regulatory Effects of Long Non-coding RNAs on Th17/Treg Differentiation and Imbalance.
In: Iranian Journal of Allergy, Asthma & Immunology, Jg. 22 (2023-12-01), Heft 6, S. 512-526
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Zugriff:
Scientific research over the past decades has proven the pivotal role of long non-coding RNAs (LncRNAs) in regulating gene expression. The immune responses are controlled through the interaction of pro-inflammatory (predominance of T helper 17 cells (Th17)) and anti-inflammatory cytokines excretion (predominance of Regulatory T cells (Treg)). Recent studies have marked the impact of many diverse LncRNAs on Treg/Th17 imbalances. Moreover, some of the roots and causes of human diseases can be associated with the alterations in the Th17/Treg ratio. In this review study, we overviewed the association between LncRNAs and Th17/Treg, with the potential of providing novel prognostic and diagnostic biomarkers and promising therapeutic targets in various diseases, particularly cancer. [ABSTRACT FROM AUTHOR]
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Titel: |
Regulatory Effects of Long Non-coding RNAs on Th17/Treg Differentiation and Imbalance.
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Autor/in / Beteiligte Person: | Dabbaghipour, Reza ; Ahmadi, Elham ; Entezam, Mona ; Farzam, Omid Rahbar ; Baghbanzadeh, Amir ; Sichani, Ali Saber ; Jalilzadeh, Nazila ; Jafarlou, Mahdi ; Baradaran, Behzad |
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Zeitschrift: | Iranian Journal of Allergy, Asthma & Immunology, Jg. 22 (2023-12-01), Heft 6, S. 512-526 |
Veröffentlichung: | 2023 |
Medientyp: | academicJournal |
ISSN: | 1735-1502 (print) |
DOI: | 10.18502/ijaai.v22i6.14641 |
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