Menofia University Researchers Describe Findings in Adenocarcinoma (Diagnostic and prognostic significance of tissue lncRNA HOTAIR and hexokinase 2 mRNA expression in patients with pancreatic ductal adenocarcinoma).

A recent report from Menofia University discusses the diagnostic and prognostic potential of two markers, long non-coding RNA HOTAIR and the glycolytic enzyme hexokinase 2 (HK2) mRNA, in pancreatic ductal adenocarcinoma. The study found that both markers were significantly increased in tumorous pancreatic tissues compared to non-tumorous tissue. Additionally, elevated levels of these markers were associated with shorter median survival and increased risk of adverse outcomes or recurrence. The findings suggest that lncRNA HOTAIR and HK2 expression levels could serve as diagnostic and prognostic indicators in pancreatic cancer. [Extracted from the article]

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