Studies from Sichuan University in the Area of Rheumatoid Arthritis Described (A Less-is-more Strategy for Mitochondria-targeted Photodynamic Therapy of Rheumatoid Arthritis).

A recent study conducted at Sichuan University in China explores a new approach to photodynamic therapy (PDT) for rheumatoid arthritis (RA). The researchers propose a "less-is-more" strategy by targeting mitochondria to achieve higher apoptosis in pro-inflammatory cells using lower laser power. The study found that mitochondria-targeting liposomes effectively disrupted mitochondria in pro-inflammatory macrophages, leading to increased apoptosis initiation. This approach shows promise in reconciling therapeutic efficacy and inflammation, offering a potential solution to the dilemma faced by conventional PDT for RA. [Extracted from the article]

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