New Interleukin Receptors Findings from Department of Clinical Cancer Prevention Outlined (Gut Epithelial Interleukin-17 Receptor a Signaling Can Modulate Distant Tumors Growth Through Microbial Regulation).

A recent study published in Cancer Weekly explores the role of gut epithelial interleukin-17 receptor a (IL-17RA) signaling in modulating the growth of distant tumors through microbial regulation. The research suggests that IL-17 signaling contributes to gut barrier immunity by regulating microbes, but also drives tumor growth. The study demonstrates that gut dysbiosis induced by systemic or gut epithelial deletion of IL-17RA leads to the excessive development of Th17 cells and B cells, which promote tumor growth. The findings highlight the complexities of IL-17-IL-17RA signaling and its relevance in cancer therapy. [Extracted from the article]

Copyright of Cancer Weekly is the property of NewsRx and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)