肠道微生态与自身免疫性肝炎发生发展的关系. (Chinese)

Autoimmune hepatitis (AIH) is an autoimmune disease characterized by chronic liver inflammation, with a gradually increasing incidence rate, and its social and medical burdens cannot be neglected. Intestinal microecology is becoming a research hotspot in the field of autoimmune disease. In recent years, it has been believed that changes in intestinal microecology can cause changes in autoimmune state, microbial metabolites, and intestinal barrier, which is one of the driving factors for the onset of AIH. Early diagnosis and correct treatment can help to improve the prognosis of AIH patients. This article introduces the characteristics of gut microbiota in AIH patients, elaborates on the impact of intestinal microflora imbalance on the pathogenesis of AIH, and briefly describes related treatment regimens from the perspective of intestinal microecology, so as to comprehensively understand and explain the role of intestinal microecology in AIH and the impact of intestinal microecology balance on the pathogenesis, diagnosis, and treatment of AIH. [ABSTRACT FROM AUTHOR]

自身免疫性肝炎（AIH）是以慢性肝脏炎症为特点的自身免疫性疾病，发病率逐年升高，社会医疗负担不容小视。肠 道微生态正成为自身免疫性疾病研究的热点。近年来认为肠道微生态的改变会引起自身免疫状态、菌群代谢产物和肠道 屏障的改变，是AIH发病的驱动因素之一。早期诊断和正确的治疗有助于改善AIH患者的预后。本文介绍了AIH患者肠 道菌群的特点、肠道微生态失衡对AIH发病机制的影响以及从肠道微生态角度出发简述了相关治疗方案，旨在全面理解和 解释肠道微生态在AIH中的作用，了解肠道微生态平衡对AIH致病机制、诊断和治疗的影响。 [ABSTRACT FROM AUTHOR]

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