Researchers Submit Patent Application, "Mhc Class I Associated Peptides For Prevention And Treatment Of Multiple Flavi Virus", for Approval (USPTO 20240050548).

A patent application has been submitted for a vaccine composition that aims to stimulate an immune response against multiple species of flavivirus, including Zika virus, Dengue virus, West Nile virus, yellow fever virus, and Japanese encephalitis virus. The vaccine composition utilizes a nanoparticle, such as a gold nanoparticle, to induce a T cell response without the need for a virus or traditional adjuvant. The composition includes conserved peptides that bind to different HLA supertypes, making it effective in individuals with different HLA types. This invention addresses the need for effective vaccines against flavivirus infections, as current vaccines are limited in their coverage and potential adverse effects. [Extracted from the article]

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